Maternal adiposity and maternal and cord blood concentrations of vitamin D [25(OH)D3]
Obesity is associated with lower concentrations of vitamin D [25(OH)D3] in children, adolescents and adults, but it remains unclear whether maternal adiposity influences maternal and foetal concentrations of this vitamin. The objective of this cross-sectional study was to assess the relationship bet...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-10-01
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| Series: | Clinical Nutrition Experimental |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352939316300239 |
| _version_ | 1818133363587809280 |
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| author | Fernanda F.A. Simões Natália P. Castro Verônica V. Euclydes Liania A. Luzia Adriana A. Paiva Patrícia H.C. Rondó |
| author_facet | Fernanda F.A. Simões Natália P. Castro Verônica V. Euclydes Liania A. Luzia Adriana A. Paiva Patrícia H.C. Rondó |
| author_sort | Fernanda F.A. Simões |
| collection | DOAJ |
| description | Obesity is associated with lower concentrations of vitamin D [25(OH)D3] in children, adolescents and adults, but it remains unclear whether maternal adiposity influences maternal and foetal concentrations of this vitamin. The objective of this cross-sectional study was to assess the relationship between maternal adiposity and maternal and cord blood concentrations of vitamin D. It involved 101 mother–newborn pairs from a public maternity in Sao Paulo city, Brazil. Demographic, socioeconomic and obstetric data, as well as anthropometry, physical activity and vitamin D supplementation during pregnancy, were investigated. Maternal adiposity was assessed by bioelectrical impedance. Maternal and cord blood concentrations of vitamin D were measured by high-performance liquid chromatography. Two multiple linear regression models that included maternal and cord blood vitamin D concentrations as outcomes and maternal adiposity as independent variable were used. No association was observed between maternal adiposity and maternal or cord blood concentrations of vitamin D. Maternal vitamin D concentration was associated with race, physical activity and vitamin D supplementation (adj. R2 = 0.74). Cord blood vitamin D concentration was associated with maternal vitamin D concentration (adj. R2 = 0.24). Although fat mass quantification is important to understand vitamin D status during all stages of life, this may not be true in pregnancy as race, vitamin D supplementation and physical activity appeared to be more relevant to vitamin D status. Understanding vitamin D metabolism in pregnancy may elucidate how or if adiposity influences maternal vitamin D status and how it impacts vitamin D transport to the foetus. |
| first_indexed | 2024-12-11T08:51:32Z |
| format | Article |
| id | doaj.art-7893dd2de81b4e54b5c9875eff11c016 |
| institution | Directory Open Access Journal |
| issn | 2352-9393 |
| language | English |
| last_indexed | 2024-12-11T08:51:32Z |
| publishDate | 2016-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical Nutrition Experimental |
| spelling | doaj.art-7893dd2de81b4e54b5c9875eff11c0162022-12-22T01:14:00ZengElsevierClinical Nutrition Experimental2352-93932016-10-019C31210.1016/j.yclnex.2016.08.001Maternal adiposity and maternal and cord blood concentrations of vitamin D [25(OH)D3]Fernanda F.A. Simões0Natália P. Castro1Verônica V. Euclydes2Liania A. Luzia3Adriana A. Paiva4Patrícia H.C. Rondó5Nutrition Department, School of Public Health, University of São Paulo, BrazilNutrition Department, School of Public Health, University of São Paulo, BrazilPostgraduate Program in Applied Human Nutrition (PRONUT), University of São Paulo, BrazilNutrition Department, School of Public Health, University of São Paulo, BrazilNutrition Department, Federal University of Piauí, BrazilNutrition Department, School of Public Health, University of São Paulo, BrazilObesity is associated with lower concentrations of vitamin D [25(OH)D3] in children, adolescents and adults, but it remains unclear whether maternal adiposity influences maternal and foetal concentrations of this vitamin. The objective of this cross-sectional study was to assess the relationship between maternal adiposity and maternal and cord blood concentrations of vitamin D. It involved 101 mother–newborn pairs from a public maternity in Sao Paulo city, Brazil. Demographic, socioeconomic and obstetric data, as well as anthropometry, physical activity and vitamin D supplementation during pregnancy, were investigated. Maternal adiposity was assessed by bioelectrical impedance. Maternal and cord blood concentrations of vitamin D were measured by high-performance liquid chromatography. Two multiple linear regression models that included maternal and cord blood vitamin D concentrations as outcomes and maternal adiposity as independent variable were used. No association was observed between maternal adiposity and maternal or cord blood concentrations of vitamin D. Maternal vitamin D concentration was associated with race, physical activity and vitamin D supplementation (adj. R2 = 0.74). Cord blood vitamin D concentration was associated with maternal vitamin D concentration (adj. R2 = 0.24). Although fat mass quantification is important to understand vitamin D status during all stages of life, this may not be true in pregnancy as race, vitamin D supplementation and physical activity appeared to be more relevant to vitamin D status. Understanding vitamin D metabolism in pregnancy may elucidate how or if adiposity influences maternal vitamin D status and how it impacts vitamin D transport to the foetus.http://www.sciencedirect.com/science/article/pii/S2352939316300239AdiposityVitamin DNewbornMotherCord blood |
| spellingShingle | Fernanda F.A. Simões Natália P. Castro Verônica V. Euclydes Liania A. Luzia Adriana A. Paiva Patrícia H.C. Rondó Maternal adiposity and maternal and cord blood concentrations of vitamin D [25(OH)D3] Clinical Nutrition Experimental Adiposity Vitamin D Newborn Mother Cord blood |
| title | Maternal adiposity and maternal and cord blood concentrations of vitamin D [25(OH)D3] |
| title_full | Maternal adiposity and maternal and cord blood concentrations of vitamin D [25(OH)D3] |
| title_fullStr | Maternal adiposity and maternal and cord blood concentrations of vitamin D [25(OH)D3] |
| title_full_unstemmed | Maternal adiposity and maternal and cord blood concentrations of vitamin D [25(OH)D3] |
| title_short | Maternal adiposity and maternal and cord blood concentrations of vitamin D [25(OH)D3] |
| title_sort | maternal adiposity and maternal and cord blood concentrations of vitamin d 25 oh d3 |
| topic | Adiposity Vitamin D Newborn Mother Cord blood |
| url | http://www.sciencedirect.com/science/article/pii/S2352939316300239 |
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