Lentinan inhibits tumor angiogenesis via interferon γ and in a T cell independent manner

Lentinan inhibits tumor angiogenesis via interferon γ and in a T cell independent manner

Abstract Background Antiangiogenic agents are commonly used in lung and colon cancer treatments, however, rapid development of drug resistance limits their efficacy. Methods Lentinan (LNT) is a biologically active compound extracted from Lentinus edodes. The effects of LNT on tumor angiogenesis were...

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Bibliographic Details
Main Authors: Shengming Deng, Guoxi Zhang, Jiajie Kuai, Peng Fan, Xuexiang Wang, Pei Zhou, Dan Yang, Xichen Zheng, Xiaomei Liu, Qunli Wu, Yuhui Huang
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Lentinan
Interferon γ
Antiangiogenic therapy
Drug resistance
Lung cancer
Online Access:http://link.springer.com/article/10.1186/s13046-018-0932-y

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