The ferroptosis and iron-metabolism signature robustly predicts clinical diagnosis, prognosis and immune microenvironment for hepatocellular carcinoma

The ferroptosis and iron-metabolism signature robustly predicts clinical diagnosis, prognosis and immune microenvironment for hepatocellular carcinoma

Abstract Background In this study, we comprehensively analyzed genes related to ferroptosis and iron metabolism to construct diagnostic and prognostic models and explore the relationship with the immune microenvironment in HCC. Methods Integrated analysis, cox regression and the least absolute shrin...

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Bibliographic Details
Main Authors: Bufu Tang, Jinyu Zhu, Jie Li, Kai Fan, Yang Gao, Shimiao Cheng, Chunli Kong, Liyun Zheng, Fazong Wu, Qiaoyou Weng, Chenying Lu, Jiansong Ji
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Cell Communication and Signaling
Subjects:
Ferroptosis
Hepatocellular carcinoma (HCC)
TMB
Immune microenvironment
Prognosis
Online Access:http://link.springer.com/article/10.1186/s12964-020-00663-1

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