A review on potential roles of vitamins in incidence, progression, and improvement of multiple sclerosis

Multiple Sclerosis (MS) is an inflammatory and neurodegenerative disease, with unknown etiology. Vitamins, as important micronutrients playing different roles in body, seem to be important in MS pathogenesis. In vitro, in vivo and human studies, supports the protective role of some vitamins in MS oc...

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Main Authors: Matin Khosravi-Largani, Parmida Pourvali-Talatappeh, Ali Mohammad Rousta, Maedeh Karimi-Kivi, Elahe Noroozi, Ali Mahjoob, Yasaman Asaadi, Alireza Shahmohammadi, Sarina Sadeghi, Shiva Shakeri, Kimiya Ghiyasvand, Masoumeh Tavakoli-Yaraki
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:eNeurologicalSci
Online Access:http://www.sciencedirect.com/science/article/pii/S2405650218300078
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author Matin Khosravi-Largani
Parmida Pourvali-Talatappeh
Ali Mohammad Rousta
Maedeh Karimi-Kivi
Elahe Noroozi
Ali Mahjoob
Yasaman Asaadi
Alireza Shahmohammadi
Sarina Sadeghi
Shiva Shakeri
Kimiya Ghiyasvand
Masoumeh Tavakoli-Yaraki
author_facet Matin Khosravi-Largani
Parmida Pourvali-Talatappeh
Ali Mohammad Rousta
Maedeh Karimi-Kivi
Elahe Noroozi
Ali Mahjoob
Yasaman Asaadi
Alireza Shahmohammadi
Sarina Sadeghi
Shiva Shakeri
Kimiya Ghiyasvand
Masoumeh Tavakoli-Yaraki
author_sort Matin Khosravi-Largani
collection DOAJ
description Multiple Sclerosis (MS) is an inflammatory and neurodegenerative disease, with unknown etiology. Vitamins, as important micronutrients playing different roles in body, seem to be important in MS pathogenesis. In vitro, in vivo and human studies, supports the protective role of some vitamins in MS occurrence or progression. Current study reviews recent insights and reports about the importance of vitamins in MS incidence or progression. In accordance, the importance of all water and fat-soluble vitamins in MS pathogenesis based on observational studies in human population and their role in the function of immune system as well as possible therapeutic opportunities are discussed in depth throughout this review. Keywords: Multiple sclerosis, Experimental autoimmune encephalomyelitis, Vitamin A, Vitamin E, Vitamin D, Folic acid, Vitamin B 12, Vitamins
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spelling doaj.art-789a2cc9bcd249d3a34083419a3cfee82022-12-22T02:32:43ZengElseviereNeurologicalSci2405-65022018-03-01103744A review on potential roles of vitamins in incidence, progression, and improvement of multiple sclerosisMatin Khosravi-Largani0Parmida Pourvali-Talatappeh1Ali Mohammad Rousta2Maedeh Karimi-Kivi3Elahe Noroozi4Ali Mahjoob5Yasaman Asaadi6Alireza Shahmohammadi7Sarina Sadeghi8Shiva Shakeri9Kimiya Ghiyasvand10Masoumeh Tavakoli-Yaraki11School of Medicine, Iran University of Medical Sciences, Tehran, Iran; Correspondence to: M. Khosravi-Largani, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.School of Medicine, Iran University of Medical Sciences, Tehran, IranSchool of Medicine, Iran University of Medical Sciences, Tehran, IranSchool of Medicine, Iran University of Medical Sciences, Tehran, IranSchool of Medicine, Iran University of Medical Sciences, Tehran, IranSchool of Medicine, Iran University of Medical Sciences, Tehran, IranDepartment of Biotechnology, College of Science, University of Tehran, Tehran, IranSchool of Medicine, Iran University of Medical Sciences, Tehran, IranSchool of Medicine, Iran University of Medical Sciences, Tehran, IranSchool of Medicine, Iran University of Medical Sciences, Tehran, IranSchool of Medicine, Iran University of Medical Sciences, Tehran, IranDepartment of Biochemistry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran; Correspondence to: Masoumeh Tavakoli-Yaraki, Department of Biochemistry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.Multiple Sclerosis (MS) is an inflammatory and neurodegenerative disease, with unknown etiology. Vitamins, as important micronutrients playing different roles in body, seem to be important in MS pathogenesis. In vitro, in vivo and human studies, supports the protective role of some vitamins in MS occurrence or progression. Current study reviews recent insights and reports about the importance of vitamins in MS incidence or progression. In accordance, the importance of all water and fat-soluble vitamins in MS pathogenesis based on observational studies in human population and their role in the function of immune system as well as possible therapeutic opportunities are discussed in depth throughout this review. Keywords: Multiple sclerosis, Experimental autoimmune encephalomyelitis, Vitamin A, Vitamin E, Vitamin D, Folic acid, Vitamin B 12, Vitaminshttp://www.sciencedirect.com/science/article/pii/S2405650218300078
spellingShingle Matin Khosravi-Largani
Parmida Pourvali-Talatappeh
Ali Mohammad Rousta
Maedeh Karimi-Kivi
Elahe Noroozi
Ali Mahjoob
Yasaman Asaadi
Alireza Shahmohammadi
Sarina Sadeghi
Shiva Shakeri
Kimiya Ghiyasvand
Masoumeh Tavakoli-Yaraki
A review on potential roles of vitamins in incidence, progression, and improvement of multiple sclerosis
eNeurologicalSci
title A review on potential roles of vitamins in incidence, progression, and improvement of multiple sclerosis
title_full A review on potential roles of vitamins in incidence, progression, and improvement of multiple sclerosis
title_fullStr A review on potential roles of vitamins in incidence, progression, and improvement of multiple sclerosis
title_full_unstemmed A review on potential roles of vitamins in incidence, progression, and improvement of multiple sclerosis
title_short A review on potential roles of vitamins in incidence, progression, and improvement of multiple sclerosis
title_sort review on potential roles of vitamins in incidence progression and improvement of multiple sclerosis
url http://www.sciencedirect.com/science/article/pii/S2405650218300078
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