A rare case of haemolytic disease of newborn with Bombay phenotype mother
We are reporting a rare case of severe hemolytic disease of newborn (HDN) with Bombay phenotype mother. A retrospective study of a case with severe haemolytic disease of newborn with Bombay phenotype mother was done. Blood grouping, antibody screening, and lectin study was done on the blood sample o...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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Series: | Asian Journal of Transfusion Science |
Subjects: | |
Online Access: | http://www.ajts.org/article.asp?issn=0973-6247;year=2013;volume=7;issue=2;spage=153;epage=155;aulast=Shastry |
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author | Shamee Shastry Leslie E Lewis Sudha S Bhat |
author_facet | Shamee Shastry Leslie E Lewis Sudha S Bhat |
author_sort | Shamee Shastry |
collection | DOAJ |
description | We are reporting a rare case of severe hemolytic disease of newborn (HDN) with Bombay phenotype mother. A retrospective study of a case with severe haemolytic disease of newborn with Bombay phenotype mother was done. Blood grouping, antibody screening, and lectin study was done on the blood sample of the baby and mother to confirm the diagnosis. Hematological and biochemical parameters were obtained from the hospital laboratory information system for the analysis. Blood group of the baby was A positive, direct antiglobulin test was negative. Blood group of the mother was confirmed to be Bombay phenotype, Hematological parameters showed all the signs of ongoing hemolysis and the bilirubin level was in the zone of exchange transfusion. Due to the unavailability of this rare phenotype blood unit, baby was managed conservatively. Anticipating the fetal anemia and HDN with mothers having Bombay phenotype and prior notification to the transfusion services will be of great help in optimizing the neonatal care and outcome. |
first_indexed | 2024-04-14T02:15:16Z |
format | Article |
id | doaj.art-789a372c8e79466f9e866f2d96f2fa3b |
institution | Directory Open Access Journal |
issn | 0973-6247 1998-3565 |
language | English |
last_indexed | 2024-04-14T02:15:16Z |
publishDate | 2013-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Asian Journal of Transfusion Science |
spelling | doaj.art-789a372c8e79466f9e866f2d96f2fa3b2022-12-22T02:18:12ZengWolters Kluwer Medknow PublicationsAsian Journal of Transfusion Science0973-62471998-35652013-01-017215315510.4103/0973-6247.115583A rare case of haemolytic disease of newborn with Bombay phenotype motherShamee ShastryLeslie E LewisSudha S BhatWe are reporting a rare case of severe hemolytic disease of newborn (HDN) with Bombay phenotype mother. A retrospective study of a case with severe haemolytic disease of newborn with Bombay phenotype mother was done. Blood grouping, antibody screening, and lectin study was done on the blood sample of the baby and mother to confirm the diagnosis. Hematological and biochemical parameters were obtained from the hospital laboratory information system for the analysis. Blood group of the baby was A positive, direct antiglobulin test was negative. Blood group of the mother was confirmed to be Bombay phenotype, Hematological parameters showed all the signs of ongoing hemolysis and the bilirubin level was in the zone of exchange transfusion. Due to the unavailability of this rare phenotype blood unit, baby was managed conservatively. Anticipating the fetal anemia and HDN with mothers having Bombay phenotype and prior notification to the transfusion services will be of great help in optimizing the neonatal care and outcome.http://www.ajts.org/article.asp?issn=0973-6247;year=2013;volume=7;issue=2;spage=153;epage=155;aulast=ShastryBlood groupingBombay phenotypehemolytic disease of newborn |
spellingShingle | Shamee Shastry Leslie E Lewis Sudha S Bhat A rare case of haemolytic disease of newborn with Bombay phenotype mother Asian Journal of Transfusion Science Blood grouping Bombay phenotype hemolytic disease of newborn |
title | A rare case of haemolytic disease of newborn with Bombay phenotype mother |
title_full | A rare case of haemolytic disease of newborn with Bombay phenotype mother |
title_fullStr | A rare case of haemolytic disease of newborn with Bombay phenotype mother |
title_full_unstemmed | A rare case of haemolytic disease of newborn with Bombay phenotype mother |
title_short | A rare case of haemolytic disease of newborn with Bombay phenotype mother |
title_sort | rare case of haemolytic disease of newborn with bombay phenotype mother |
topic | Blood grouping Bombay phenotype hemolytic disease of newborn |
url | http://www.ajts.org/article.asp?issn=0973-6247;year=2013;volume=7;issue=2;spage=153;epage=155;aulast=Shastry |
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