A rare case of haemolytic disease of newborn with Bombay phenotype mother

We are reporting a rare case of severe hemolytic disease of newborn (HDN) with Bombay phenotype mother. A retrospective study of a case with severe haemolytic disease of newborn with Bombay phenotype mother was done. Blood grouping, antibody screening, and lectin study was done on the blood sample o...

Full description

Bibliographic Details
Main Authors: Shamee Shastry, Leslie E Lewis, Sudha S Bhat
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Asian Journal of Transfusion Science
Subjects:
Online Access:http://www.ajts.org/article.asp?issn=0973-6247;year=2013;volume=7;issue=2;spage=153;epage=155;aulast=Shastry
_version_ 1817995985801969664
author Shamee Shastry
Leslie E Lewis
Sudha S Bhat
author_facet Shamee Shastry
Leslie E Lewis
Sudha S Bhat
author_sort Shamee Shastry
collection DOAJ
description We are reporting a rare case of severe hemolytic disease of newborn (HDN) with Bombay phenotype mother. A retrospective study of a case with severe haemolytic disease of newborn with Bombay phenotype mother was done. Blood grouping, antibody screening, and lectin study was done on the blood sample of the baby and mother to confirm the diagnosis. Hematological and biochemical parameters were obtained from the hospital laboratory information system for the analysis. Blood group of the baby was A positive, direct antiglobulin test was negative. Blood group of the mother was confirmed to be Bombay phenotype, Hematological parameters showed all the signs of ongoing hemolysis and the bilirubin level was in the zone of exchange transfusion. Due to the unavailability of this rare phenotype blood unit, baby was managed conservatively. Anticipating the fetal anemia and HDN with mothers having Bombay phenotype and prior notification to the transfusion services will be of great help in optimizing the neonatal care and outcome.
first_indexed 2024-04-14T02:15:16Z
format Article
id doaj.art-789a372c8e79466f9e866f2d96f2fa3b
institution Directory Open Access Journal
issn 0973-6247
1998-3565
language English
last_indexed 2024-04-14T02:15:16Z
publishDate 2013-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Asian Journal of Transfusion Science
spelling doaj.art-789a372c8e79466f9e866f2d96f2fa3b2022-12-22T02:18:12ZengWolters Kluwer Medknow PublicationsAsian Journal of Transfusion Science0973-62471998-35652013-01-017215315510.4103/0973-6247.115583A rare case of haemolytic disease of newborn with Bombay phenotype motherShamee ShastryLeslie E LewisSudha S BhatWe are reporting a rare case of severe hemolytic disease of newborn (HDN) with Bombay phenotype mother. A retrospective study of a case with severe haemolytic disease of newborn with Bombay phenotype mother was done. Blood grouping, antibody screening, and lectin study was done on the blood sample of the baby and mother to confirm the diagnosis. Hematological and biochemical parameters were obtained from the hospital laboratory information system for the analysis. Blood group of the baby was A positive, direct antiglobulin test was negative. Blood group of the mother was confirmed to be Bombay phenotype, Hematological parameters showed all the signs of ongoing hemolysis and the bilirubin level was in the zone of exchange transfusion. Due to the unavailability of this rare phenotype blood unit, baby was managed conservatively. Anticipating the fetal anemia and HDN with mothers having Bombay phenotype and prior notification to the transfusion services will be of great help in optimizing the neonatal care and outcome.http://www.ajts.org/article.asp?issn=0973-6247;year=2013;volume=7;issue=2;spage=153;epage=155;aulast=ShastryBlood groupingBombay phenotypehemolytic disease of newborn
spellingShingle Shamee Shastry
Leslie E Lewis
Sudha S Bhat
A rare case of haemolytic disease of newborn with Bombay phenotype mother
Asian Journal of Transfusion Science
Blood grouping
Bombay phenotype
hemolytic disease of newborn
title A rare case of haemolytic disease of newborn with Bombay phenotype mother
title_full A rare case of haemolytic disease of newborn with Bombay phenotype mother
title_fullStr A rare case of haemolytic disease of newborn with Bombay phenotype mother
title_full_unstemmed A rare case of haemolytic disease of newborn with Bombay phenotype mother
title_short A rare case of haemolytic disease of newborn with Bombay phenotype mother
title_sort rare case of haemolytic disease of newborn with bombay phenotype mother
topic Blood grouping
Bombay phenotype
hemolytic disease of newborn
url http://www.ajts.org/article.asp?issn=0973-6247;year=2013;volume=7;issue=2;spage=153;epage=155;aulast=Shastry
work_keys_str_mv AT shameeshastry ararecaseofhaemolyticdiseaseofnewbornwithbombayphenotypemother
AT leslieelewis ararecaseofhaemolyticdiseaseofnewbornwithbombayphenotypemother
AT sudhasbhat ararecaseofhaemolyticdiseaseofnewbornwithbombayphenotypemother
AT shameeshastry rarecaseofhaemolyticdiseaseofnewbornwithbombayphenotypemother
AT leslieelewis rarecaseofhaemolyticdiseaseofnewbornwithbombayphenotypemother
AT sudhasbhat rarecaseofhaemolyticdiseaseofnewbornwithbombayphenotypemother