Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: A tangible union against chemoresistant cancer

Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: A tangible union against chemoresistant cancer

<p>Abstract</p> <p>Background</p> <p>Late stage Ovarian Cancer is essentially incurable primarily due to late diagnosis and its inherent heterogeneity. Single agent treatments are inadequate and generally lead to severe side effects at therapeutic doses. It is crucial t...

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Bibliographic Details
Main Authors:	Joshi Swapna, Singh Preetinder P, Russell Pamela J, Nair Sham, Khatri Aparajita
Format:	Article
Language:	English
Published:	BMC 2011-08-01
Series:	BMC Cancer
Subjects:	Chemotherapy Molecular chemotherapy Purine nucleoside phosphorylase (PNP) Fludarabine Phosphate (Fludara) Gene directed enzyme prodrug therapy (GDEPT) Ovarian cancer Cancer
Online Access:	http://www.biomedcentral.com/1471-2407/11/368

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