Involvement of microRNA-138-5p in cardiac surgery-induced postoperative cognitive dysfunction

Involvement of microRNA-138-5p in cardiac surgery-induced postoperative cognitive dysfunction

Background: Despite being one of the main concerns in cardiac surgery, the molecular basis and regulatory mechanisms of postoperative cognitive dysfunction (POCD) are still unclear. In this study, we demonstrate the critical role of miR-138-5p in POCD in mice. Methods: We first established an an...

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Bibliographic Details
Main Authors: Pavan Bandhu, Kartik Das
Format: Article
Language:English
Published: Innovation Publishing House Pte. Ltd. 2023-04-01
Series:STEMedicine
Subjects:
postoperative cognition dysfunction
miR-138-5p
cardiac surgery
sirtuin 1
hippocampus
Online Access:http://stemedicine.org/index.php/stem/article/view/163

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