Modeling the renoprotective mechanisms of SGLT2 inhibition in hypertensive chronic kidney disease

Abstract Sodium‐glucose cotransporter (SGLT)‐2 inhibitors have recently been approved for chronic kidney disease (CKD) based on their ability to lower proteinuria and slow CKD progression independent of diabetes status. In diabetic renal disease, modulation of tubuloglomerular feedback (TGF) leading...

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Bibliographic Details
Main Authors: John S. Clemmer, Timothy E. Yen, Yoshitsugu Obi
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15836