A systematic review of blunt abdominal aortic injury and analysis of predictors of death
At present, research on blunt abdominal aortic injury (BAAI) is limited, with the majority being case reports. Consequently, there is a significant knowledge gap concerning this condition. To address this, we conducted a systematic review by extensively searching major databases. We included all li...
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| Format: | Article |
| Language: | English |
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Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2023-10-01
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| Series: | Biomolecules & Biomedicine |
| Subjects: | |
| Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/9831 |
| _version_ | 1827317518241366016 |
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| author | Mingxuan Li Chaonan Wang Haixia Tu Haitao Zhu Zhen Guo Lianrui Guo |
| author_facet | Mingxuan Li Chaonan Wang Haixia Tu Haitao Zhu Zhen Guo Lianrui Guo |
| author_sort | Mingxuan Li |
| collection | DOAJ |
| description |
At present, research on blunt abdominal aortic injury (BAAI) is limited, with the majority being case reports. Consequently, there is a significant knowledge gap concerning this condition. To address this, we conducted a systematic review by extensively searching major databases. We included all literature that provided individual (non-identifiable) data on BAAI patients, irrespective of the study design. Furthermore, we undertook regression analyses to identify predictors of death after BAAI. The search yielded 2,099 results, leading to the inclusion of 102 case reports and one conference abstract. Using the Joanna Briggs Institute (JBI) checklist for assessment, all studies were deemed of medium to high quality. In total, 133 patients were included, with a median age of 34 years, and 73.7% being male. The predominant clinical manifestation was pain, reported in 65.6% of patients. The most frequently observed aortic lesion severity was grade A (intimal tear or intramural hematoma) at 46.9%, and the most common lesion location was zone III (infrarenal aorta) in 88.3% of cases. The overall mortality after BAAI was 15.3%. Multivariate regression analyses revealed the following predictors of death after BAAI: lower limb ischemia (relative risk [RR] = 7.137, 95% confidence interval [CI] 1.154 - 44.161), cardiopulmonary arrest (RR = 10.250, 95% CI 1.452 - 72.344), and injuries to body parts other than the abdomen and lumbar spine (RR = 2.593, 95% CI 1.189 - 5.655). In conclusion, this review provides a detailed quantitative summary of BAAI's clinical manifestations, diagnosis, treatment, and prognosis, emphasizing its high mortality rate and identifying three critical variables as predictors of death.
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| first_indexed | 2024-04-24T23:40:10Z |
| format | Article |
| id | doaj.art-78a8795be8d74d42afe86605ff519301 |
| institution | Directory Open Access Journal |
| issn | 2831-0896 2831-090X |
| language | English |
| last_indexed | 2024-04-24T23:40:10Z |
| publishDate | 2023-10-01 |
| publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
| record_format | Article |
| series | Biomolecules & Biomedicine |
| spelling | doaj.art-78a8795be8d74d42afe86605ff5193012024-03-15T13:22:22ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2023-10-0110.17305/bb.2023.9831A systematic review of blunt abdominal aortic injury and analysis of predictors of deathMingxuan Li0https://orcid.org/0000-0002-0473-5667Chaonan Wang1https://orcid.org/0009-0005-5746-6500Haixia Tu2https://orcid.org/0009-0005-5746-6500Haitao Zhu3Zhen Guo4Lianrui Guo5https://orcid.org/0009-0005-5746-6500Department of Vascular Surgery, Beijing Fengtai You’anmen Hospital, Beijing, ChinaDepartment of Vascular Surgery, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Vascular Surgery, Beijing Fengtai You’anmen Hospital, Beijing, ChinaDepartment of Vascular Surgery, Beijing Fengtai You’anmen Hospital, Beijing, ChinaDepartment of Vascular Surgery, Beijing Fengtai You’anmen Hospital, Beijing, ChinaDepartment of Vascular Surgery, Xuanwu Hospital Capital Medical University, Beijing, China At present, research on blunt abdominal aortic injury (BAAI) is limited, with the majority being case reports. Consequently, there is a significant knowledge gap concerning this condition. To address this, we conducted a systematic review by extensively searching major databases. We included all literature that provided individual (non-identifiable) data on BAAI patients, irrespective of the study design. Furthermore, we undertook regression analyses to identify predictors of death after BAAI. The search yielded 2,099 results, leading to the inclusion of 102 case reports and one conference abstract. Using the Joanna Briggs Institute (JBI) checklist for assessment, all studies were deemed of medium to high quality. In total, 133 patients were included, with a median age of 34 years, and 73.7% being male. The predominant clinical manifestation was pain, reported in 65.6% of patients. The most frequently observed aortic lesion severity was grade A (intimal tear or intramural hematoma) at 46.9%, and the most common lesion location was zone III (infrarenal aorta) in 88.3% of cases. The overall mortality after BAAI was 15.3%. Multivariate regression analyses revealed the following predictors of death after BAAI: lower limb ischemia (relative risk [RR] = 7.137, 95% confidence interval [CI] 1.154 - 44.161), cardiopulmonary arrest (RR = 10.250, 95% CI 1.452 - 72.344), and injuries to body parts other than the abdomen and lumbar spine (RR = 2.593, 95% CI 1.189 - 5.655). In conclusion, this review provides a detailed quantitative summary of BAAI's clinical manifestations, diagnosis, treatment, and prognosis, emphasizing its high mortality rate and identifying three critical variables as predictors of death. https://www.bjbms.org/ojs/index.php/bjbms/article/view/9831Blunt abdominal aortic injury (BAAI)blunt traumaabdominal injurymortalitytrauma |
| spellingShingle | Mingxuan Li Chaonan Wang Haixia Tu Haitao Zhu Zhen Guo Lianrui Guo A systematic review of blunt abdominal aortic injury and analysis of predictors of death Biomolecules & Biomedicine Blunt abdominal aortic injury (BAAI) blunt trauma abdominal injury mortality trauma |
| title | A systematic review of blunt abdominal aortic injury and analysis of predictors of death |
| title_full | A systematic review of blunt abdominal aortic injury and analysis of predictors of death |
| title_fullStr | A systematic review of blunt abdominal aortic injury and analysis of predictors of death |
| title_full_unstemmed | A systematic review of blunt abdominal aortic injury and analysis of predictors of death |
| title_short | A systematic review of blunt abdominal aortic injury and analysis of predictors of death |
| title_sort | systematic review of blunt abdominal aortic injury and analysis of predictors of death |
| topic | Blunt abdominal aortic injury (BAAI) blunt trauma abdominal injury mortality trauma |
| url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/9831 |
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