Drug-Resistant Aerobic Bacterial Pathogens in Patients with Crocodile Bite Wounds Attending at Arba Minch General Hospital, Southern Ethiopia
Dagninet Alelign,1 Teshome Tena,2 Moges Tessema,2 Aschalew Kidanewold1 1Department of Medical Laboratory Science, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia; 2School of Medicine, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Eth...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2022-12-01
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| Series: | International Journal of General Medicine |
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| Online Access: | https://www.dovepress.com/drug-resistant-aerobic-bacterial-pathogens-in-patients-with-crocodile--peer-reviewed-fulltext-article-IJGM |
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| author | Alelign D Tena T Tessema M Kidanewold A |
| author_facet | Alelign D Tena T Tessema M Kidanewold A |
| author_sort | Alelign D |
| collection | DOAJ |
| description | Dagninet Alelign,1 Teshome Tena,2 Moges Tessema,2 Aschalew Kidanewold1 1Department of Medical Laboratory Science, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia; 2School of Medicine, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, EthiopiaCorrespondence: Dagninet Alelign, Tel +251-964-428-118, Email dagninet.alelign@gmail.comBackground: A polymicrobial infection containing a diverse range of drug-resistant bacteria worsens the success of treatment for crocodile bite wound infection. However, there is a dearth of data in Ethiopia, where crocodile bite injuries are relatively common, particularly in the area around Lake Abaya and Lake Chamo in southern Ethiopia.Methods: A hospital-based cross-sectional study was conducted from May 1st, 2021, to April 30th, 2022, at Arba Minch General Hospital. Eleven consenting patients with crocodile bite wounds were enrolled in this study. Wound swabs were collected aseptically following microbiological procedures. The diversity and type of aerobic bacterial pathogens, and drug-resistant patterns were used to determine and characterize the nature of crocodile bite wound infections.Results: Among 11 patients with crocodile bite wounds, 72.7% (8/11) of wound samples were found to be culture-positive, with a total of 21 aerobic bacterial isolates. Gram-negative bacterial isolates were found in 57.1% (12/21). Triple-bacterial isolates were found in 62.5% (5/8) of wound samples, followed by 37.5% (3/8) of double bacterial isolates. Pseudomonas aeruginosa (n = 5), followed by Citrobacter spp. (n = 4), and coagulase-negative Staphylococci (CoNS) (n = 4) were frequently isolated bacteria. Methicillin resistance (MR-CoNS) was found in 75% of isolated CoNS. 6.7% of the isolated Enterococcus faecalis was vancomycin-resistant (VRE), while 60% of the isolated P. aeruginosa were piperacillin-resistant. Overall, 85.7% (18/21) of the isolates were found to be multidrug-resistant (MDR), with 55.6% (10/18) of them being Gram-negative MDR bacterial isolates.Conclusion: Numerous aerobic bacteria that are resistant to the majority of common antibiotics have been associated with infections in crocodile bite wounds. Thus, the key to providing empirical therapy for such wounds is detecting the drug-resistant pattern of bacterial isolates.Keywords: aerobic bacteria, crocodile bite, wound infection, Arba Minch, Ethiopia |
| first_indexed | 2024-04-12T00:52:31Z |
| format | Article |
| id | doaj.art-78adab87cd4345ae98b17c8c0260f076 |
| institution | Directory Open Access Journal |
| issn | 1178-7074 |
| language | English |
| last_indexed | 2024-04-12T00:52:31Z |
| publishDate | 2022-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of General Medicine |
| spelling | doaj.art-78adab87cd4345ae98b17c8c0260f0762022-12-22T03:54:42ZengDove Medical PressInternational Journal of General Medicine1178-70742022-12-01Volume 158669867680434Drug-Resistant Aerobic Bacterial Pathogens in Patients with Crocodile Bite Wounds Attending at Arba Minch General Hospital, Southern EthiopiaAlelign DTena TTessema MKidanewold ADagninet Alelign,1 Teshome Tena,2 Moges Tessema,2 Aschalew Kidanewold1 1Department of Medical Laboratory Science, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia; 2School of Medicine, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, EthiopiaCorrespondence: Dagninet Alelign, Tel +251-964-428-118, Email dagninet.alelign@gmail.comBackground: A polymicrobial infection containing a diverse range of drug-resistant bacteria worsens the success of treatment for crocodile bite wound infection. However, there is a dearth of data in Ethiopia, where crocodile bite injuries are relatively common, particularly in the area around Lake Abaya and Lake Chamo in southern Ethiopia.Methods: A hospital-based cross-sectional study was conducted from May 1st, 2021, to April 30th, 2022, at Arba Minch General Hospital. Eleven consenting patients with crocodile bite wounds were enrolled in this study. Wound swabs were collected aseptically following microbiological procedures. The diversity and type of aerobic bacterial pathogens, and drug-resistant patterns were used to determine and characterize the nature of crocodile bite wound infections.Results: Among 11 patients with crocodile bite wounds, 72.7% (8/11) of wound samples were found to be culture-positive, with a total of 21 aerobic bacterial isolates. Gram-negative bacterial isolates were found in 57.1% (12/21). Triple-bacterial isolates were found in 62.5% (5/8) of wound samples, followed by 37.5% (3/8) of double bacterial isolates. Pseudomonas aeruginosa (n = 5), followed by Citrobacter spp. (n = 4), and coagulase-negative Staphylococci (CoNS) (n = 4) were frequently isolated bacteria. Methicillin resistance (MR-CoNS) was found in 75% of isolated CoNS. 6.7% of the isolated Enterococcus faecalis was vancomycin-resistant (VRE), while 60% of the isolated P. aeruginosa were piperacillin-resistant. Overall, 85.7% (18/21) of the isolates were found to be multidrug-resistant (MDR), with 55.6% (10/18) of them being Gram-negative MDR bacterial isolates.Conclusion: Numerous aerobic bacteria that are resistant to the majority of common antibiotics have been associated with infections in crocodile bite wounds. Thus, the key to providing empirical therapy for such wounds is detecting the drug-resistant pattern of bacterial isolates.Keywords: aerobic bacteria, crocodile bite, wound infection, Arba Minch, Ethiopiahttps://www.dovepress.com/drug-resistant-aerobic-bacterial-pathogens-in-patients-with-crocodile--peer-reviewed-fulltext-article-IJGMaerobic bacteriacrocodile bitewound infectionarba minchethiopia |
| spellingShingle | Alelign D Tena T Tessema M Kidanewold A Drug-Resistant Aerobic Bacterial Pathogens in Patients with Crocodile Bite Wounds Attending at Arba Minch General Hospital, Southern Ethiopia International Journal of General Medicine aerobic bacteria crocodile bite wound infection arba minch ethiopia |
| title | Drug-Resistant Aerobic Bacterial Pathogens in Patients with Crocodile Bite Wounds Attending at Arba Minch General Hospital, Southern Ethiopia |
| title_full | Drug-Resistant Aerobic Bacterial Pathogens in Patients with Crocodile Bite Wounds Attending at Arba Minch General Hospital, Southern Ethiopia |
| title_fullStr | Drug-Resistant Aerobic Bacterial Pathogens in Patients with Crocodile Bite Wounds Attending at Arba Minch General Hospital, Southern Ethiopia |
| title_full_unstemmed | Drug-Resistant Aerobic Bacterial Pathogens in Patients with Crocodile Bite Wounds Attending at Arba Minch General Hospital, Southern Ethiopia |
| title_short | Drug-Resistant Aerobic Bacterial Pathogens in Patients with Crocodile Bite Wounds Attending at Arba Minch General Hospital, Southern Ethiopia |
| title_sort | drug resistant aerobic bacterial pathogens in patients with crocodile bite wounds attending at arba minch general hospital southern ethiopia |
| topic | aerobic bacteria crocodile bite wound infection arba minch ethiopia |
| url | https://www.dovepress.com/drug-resistant-aerobic-bacterial-pathogens-in-patients-with-crocodile--peer-reviewed-fulltext-article-IJGM |
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