Nanoformulations with <i>Leishmania braziliensis</i> Antigens Triggered Controlled Parasite Burden in Vaccinated Golden Hamster (<i>Mesocricetus auratus</i>) against Visceral Leishmaniasis

Nanoformulations with <i>Leishmania braziliensis</i> Antigens Triggered Controlled Parasite Burden in Vaccinated Golden Hamster (<i>Mesocricetus auratus</i>) against Visceral Leishmaniasis

Leishmaniasis is a widespread vector-borne disease in Brazil, with <i>Leishmania</i> (<i>Leishmania</i>) <i>infantum</i> as the primary etiological agent of visceral leishmaniasis (VL). Dogs are considered the main reservoir of this parasite, whose treatment in Br...

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Main Authors: Jennifer Ottino, Jaqueline Costa Leite, Otoni Alves Melo-Júnior, Marco Antonio Cabrera González, Tatiane Furtado de Carvalho, Giani Martins Garcia, Maurício Azevedo Batista, Patrícia Silveira, Mariana Santos Cardoso, Lilian Lacerda Bueno, Ricardo Toshio Fujiwara, Renato Lima Santos, Paulo Ricardo de Oliveira Paes, Denise Silveira-Lemos, Olindo Assis Martins-Filho, Alexsandro Sobreira Galdino, Miguel Angel Chávez-Fumagalli, Walderez Ornelas Dutra, Vanessa Carla Furtado Mosqueira, Rodolfo Cordeiro Giunchetti
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Vaccines
Subjects:
visceral leishmaniasis
polymeric nanoparticle
vaccine
hamster
pre-clinical trial
Online Access:https://www.mdpi.com/2076-393X/10/11/1848

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