Identification and comprehensive analysis of circRNA–miRNA–mRNA regulatory networks in osteoarthritis

Identification and comprehensive analysis of circRNA–miRNA–mRNA regulatory networks in osteoarthritis

Osteoarthritis (OA) is a common orthopedic degenerative disease, leading to high disability in activities of daily living. There remains an urgent need to identify the underlying mechanisms and identify new therapeutic targets in OA diagnosis and treatment. Circular RNAs (circRNAs) play a role in th...

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Bibliographic Details
Main Authors: Xuanzhe Liu, Huimin Xiao, Xiaotong Peng, Yimin Chai, Shuo Wang, Gen Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
circular RNA
microRNA
osteoarthritis
chondrocytes
regulatory network
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1050743/full

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