Polyclonal Antibodies Derived from Transchromosomic Bovines Vaccinated with the Recombinant F1-V Vaccine Increase Bacterial Opsonization In Vitro and Protect Mice from Pneumonic Plague

Polyclonal Antibodies Derived from Transchromosomic Bovines Vaccinated with the Recombinant F1-V Vaccine Increase Bacterial Opsonization In Vitro and Protect Mice from Pneumonic Plague

Plague is an ancient disease that continues to be of concern to both the public health and biodefense research communities. Pneumonic plague is caused by hematogenous spread of <i>Yersinia pestis</i> bacteria from a ruptured bubo to the lungs or by directly inhaling aerosolized bacteria....

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Bibliographic Details
Main Authors: Sergei S. Biryukov, Hua Wu, Jennifer L. Dankmeyer, Nathaniel O. Rill, Christopher P. Klimko, Kristi A. Egland, Jennifer L. Shoe, Melissa Hunter, David P. Fetterer, Ju Qiu, Michael L. Davies, Christoph L. Bausch, Eddie J. Sullivan, Thomas Luke, Christopher K. Cote
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Antibodies
Subjects:
<i>Yersinia pestis</i>
antibodies
transchromosomic bovine
plague
mice
opsonization
Online Access:https://www.mdpi.com/2073-4468/12/2/33

Internet

https://www.mdpi.com/2073-4468/12/2/33

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