Dark kinase annotation, mining, and visualization using the Protein Kinase Ontology

Dark kinase annotation, mining, and visualization using the Protein Kinase Ontology

The Protein Kinase Ontology (ProKinO) is an integrated knowledge graph that conceptualizes the complex relationships among protein kinase sequence, structure, function, and disease in a human and machine-readable format. In this study, we have significantly expanded ProKinO by incorporating addition...

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Bibliographic Details
Main Authors: Saber Soleymani, Nathan Gravel, Liang-Chin Huang, Wayland Yeung, Elika Bozorgi, Nathaniel G. Bendzunas, Krzysztof J. Kochut, Natarajan Kannan
Format: Article
Language:English
Published: PeerJ Inc. 2023-12-01
Series:PeerJ
Subjects:
Curation
User interface
Drug discovery
Cell signaling
Protein structure
Protein function
Online Access:https://peerj.com/articles/16087.pdf

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