Successful pharmacomechanical intervention with ultrasonic-accelerated thrombolytic catheter for massive pulmonary embolism
An 86-year-old male with history of metastatic prostate carcinoma and hypertension was admitted due to acute onset dyspnea and lower extremity pain and swelling. Transthoracic echocardiography revealed a large right atrial thrombus extending in to the right ventricle. Within 12 h, the patient develo...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2013-12-01
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| Series: | Indian Heart Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S001948321300326X |
| _version_ | 1819094794955128832 |
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| author | Mateo Porres-Aguilar Jose D. Burgos Oscar C. Munoz Ediberto Soto-Cora Debabrata Mukherjee |
| author_facet | Mateo Porres-Aguilar Jose D. Burgos Oscar C. Munoz Ediberto Soto-Cora Debabrata Mukherjee |
| author_sort | Mateo Porres-Aguilar |
| collection | DOAJ |
| description | An 86-year-old male with history of metastatic prostate carcinoma and hypertension was admitted due to acute onset dyspnea and lower extremity pain and swelling. Transthoracic echocardiography revealed a large right atrial thrombus extending in to the right ventricle. Within 12 h, the patient developed severe hypoxemia, tachypnea with sustained hypotension and cardiogenic shock due to presumed massive pulmonary embolism. The patient underwent emergency pulmonary angiography which showed large emboli in the right main pulmonary artery extending in to the middle and lower lobe branches. An ultrasonic-accelerated thrombolytic catheter was placed in the right main pulmonary artery for continuous infusion of alteplase for 20 h. Repeat pulmonary angiogram showed resolution of the large pulmonary emboli, with normal flow in to the distal pulmonary arteries. Significant improvement of hemodynamics, symptoms and hypoxemia occurred as well. |
| first_indexed | 2024-12-21T23:33:05Z |
| format | Article |
| id | doaj.art-78b990512f0843c3bdea77218d95ceef |
| institution | Directory Open Access Journal |
| issn | 0019-4832 |
| language | English |
| last_indexed | 2024-12-21T23:33:05Z |
| publishDate | 2013-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Indian Heart Journal |
| spelling | doaj.art-78b990512f0843c3bdea77218d95ceef2022-12-21T18:46:26ZengElsevierIndian Heart Journal0019-48322013-12-0165669970210.1016/j.ihj.2013.10.007Successful pharmacomechanical intervention with ultrasonic-accelerated thrombolytic catheter for massive pulmonary embolismMateo Porres-Aguilar0Jose D. Burgos1Oscar C. Munoz2Ediberto Soto-Cora3Debabrata Mukherjee4Department of Internal Medicine, Division of Hospital Medicine, Texas Tech University Health Sciences Center, Paul L. Foster School of Medicine, El Paso, TX, USADepartment of Internal Medicine, Division of Hospital Medicine, Texas Tech University Health Sciences Center, Paul L. Foster School of Medicine, El Paso, TX, USADivision of Cardiology, Del Sol Medical Center, El Paso, TX, USADivision of Cardiology, Del Sol Medical Center, El Paso, TX, USADepartment of Medicine, Chair, Division of Cardiovascular Diseases, Texas Tech University Health Sciences Center, Paul L. Foster School of Medicine, El Paso, TX, USAAn 86-year-old male with history of metastatic prostate carcinoma and hypertension was admitted due to acute onset dyspnea and lower extremity pain and swelling. Transthoracic echocardiography revealed a large right atrial thrombus extending in to the right ventricle. Within 12 h, the patient developed severe hypoxemia, tachypnea with sustained hypotension and cardiogenic shock due to presumed massive pulmonary embolism. The patient underwent emergency pulmonary angiography which showed large emboli in the right main pulmonary artery extending in to the middle and lower lobe branches. An ultrasonic-accelerated thrombolytic catheter was placed in the right main pulmonary artery for continuous infusion of alteplase for 20 h. Repeat pulmonary angiogram showed resolution of the large pulmonary emboli, with normal flow in to the distal pulmonary arteries. Significant improvement of hemodynamics, symptoms and hypoxemia occurred as well.http://www.sciencedirect.com/science/article/pii/S001948321300326XMassive pulmonary embolismPharmacomechanical thrombolysisUltrasonic-accelerated catheter-directed thrombolysisVenous thromboembolismEndovascular techniques |
| spellingShingle | Mateo Porres-Aguilar Jose D. Burgos Oscar C. Munoz Ediberto Soto-Cora Debabrata Mukherjee Successful pharmacomechanical intervention with ultrasonic-accelerated thrombolytic catheter for massive pulmonary embolism Indian Heart Journal Massive pulmonary embolism Pharmacomechanical thrombolysis Ultrasonic-accelerated catheter-directed thrombolysis Venous thromboembolism Endovascular techniques |
| title | Successful pharmacomechanical intervention with ultrasonic-accelerated thrombolytic catheter for massive pulmonary embolism |
| title_full | Successful pharmacomechanical intervention with ultrasonic-accelerated thrombolytic catheter for massive pulmonary embolism |
| title_fullStr | Successful pharmacomechanical intervention with ultrasonic-accelerated thrombolytic catheter for massive pulmonary embolism |
| title_full_unstemmed | Successful pharmacomechanical intervention with ultrasonic-accelerated thrombolytic catheter for massive pulmonary embolism |
| title_short | Successful pharmacomechanical intervention with ultrasonic-accelerated thrombolytic catheter for massive pulmonary embolism |
| title_sort | successful pharmacomechanical intervention with ultrasonic accelerated thrombolytic catheter for massive pulmonary embolism |
| topic | Massive pulmonary embolism Pharmacomechanical thrombolysis Ultrasonic-accelerated catheter-directed thrombolysis Venous thromboembolism Endovascular techniques |
| url | http://www.sciencedirect.com/science/article/pii/S001948321300326X |
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