The impact of polymorphism in PNPLA3 and TM6SF2 genes on the susceptibility and survival of hepatitis C-related hepatocellular carcinoma

The impact of polymorphism in PNPLA3 and TM6SF2 genes on the susceptibility and survival of hepatitis C-related hepatocellular carcinoma

Abstract Background Genetic variants of Patatin-like phospholipase domain-containing protein 3 (PNPLA3) and transmembrane 6 superfamily member 2 (TM6SF2) genes have been reported with the development of hepatocellular carcinoma (HCC). This study aims to explore the role of The PNPLA3 rs738409 and TM...

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Bibliographic Details
Main Authors: Samar Samir Youssef, Eman Abd El Razek Abbas, Asmaa M. Elfiky, Sameh Seif, Mohamed Mahmoud Nabeel, Hend Ibrahim Shousha, Ashraf Omar Abdelaziz
Format: Article
Language:English
Published: SpringerOpen 2022-09-01
Series:Egyptian Liver Journal
Subjects:
Hepatocellular carcinoma (HCC)
PNPLA3
TM6SF2
Single-nucleotide polymorphism
Chronic hepatitis C
Online Access:https://doi.org/10.1186/s43066-022-00212-0

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