Beyond Statins: Novel Lipid-Lowering Agents for Reducing Risk of Atherosclerotic Cardiovascular Disease

Beyond Statins: Novel Lipid-Lowering Agents for Reducing Risk of Atherosclerotic Cardiovascular Disease

Although statins have served as the cornerstone for pharmacological lowering of lipid levels in atherosclerotic cardiovascular disease (ASCVD) risk reduction, many patients are unable to achieve target doses of statin medication due to side effects or target levels of cholesterol reduction on statin...

Full description

Bibliographic Details
Main Authors:	Teimur Kayani, Bachar Ahmad, Rachel S. Chang, Frank Qian, Melis Sahinoz, Muhammad Waqar Rehan, Antonio Giaimo, Erica S. Spatz, Jiun-Ruey Hu
Format:	Article
Language:	English
Published:	MDPI AG 2024-03-01
Series:	Pharmacoepidemiology
Subjects:	cholesterol atherosclerotic cardiovascular disease statin lipid lowering randomized trials
Online Access:	https://www.mdpi.com/2813-0618/3/1/9

Similar Items

Role of statins in the management of dyslipidaemia
by: Saumitra Ray
Published: (2024-03-01)

Landscape of Statin as a Cornerstone in Atherosclerotic Cardiovascular Disease
by: Cheng Yang, et al.
Published: (2023-12-01)

The importance of LDL-C lowering in atherosclerotic cardiovascular disease prevention: Lower for longer is better
by: Omar Mhaimeed, et al.
Published: (2024-06-01)

Modeling of Mechanical Stress Exerted by Cholesterol Crystallization on Atherosclerotic Plaques
by: Luo, Yuemei, et al.
Published: (2017)

The Complex Mechanisms and the Potential Effects of Statins on Vascular Calcification: A Narrative Review
by: Nikolaos PE Kadoglou, et al.
Published: (2024-01-01)

2024 Egyptian consensus statement on the role of non-statin therapies for LDL cholesterol lowering in different patient risk categories
by: Hesham Salah El Din Taha, et al.
Published: (2024-09-01)

MicroRNA-206 as a potential cholesterol-lowering drug is superior to statins in mice
by: Chao Li, et al.
Published: (2024-07-01)

Evaluation of Statin Indication and Dose Intensification Among Type 2 Diabetic Patients at a Tertiary Hospital
by: Fisseha PY, et al.
Published: (2024-03-01)

The Immunomodulatory Effects of Statins on Macrophages
by: Alanah Sheridan, et al.
Published: (2022-04-01)

BIOCHEMICAL MARKERS OF BONE TISSUE METABOLISM INFLUENCE ON VULNERABILITY OF ATHEROSCLEROTIC LESIONS
by: Ya. N. Polonskaya, et al.
Published: (2016-11-01)

The role of statins in clinical medicine -LDL - cholesterol lowering and beyond
by: Swiss Medical Weekly
Published: (2006-01-01)

Sex specific analysis of patients with and without reported statin intolerance referred to a specialized outpatient lipid clinic
by: Maximilian A. Muck, et al.
Published: (2024-09-01)

Lipid‐Lowering Therapy Use When Indicated and Subsequent Ischemic Stroke Severity
by: Barbara Gordon‐Kundu, et al.
Published: (2025-01-01)

An Overview of the Impact of Statin Therapy on Cardiac Incident Risk
by: Urszula Świrk, et al.
Published: (2025-02-01)

Statin therapy: a potential adjuvant to immunotherapies in hepatocellular carcinoma
by: Jiao Wang, et al.
Published: (2024-02-01)

Persistent dyslipidemia in statin-treated patients: The focus on comprehensive lipid management survey in Swiss patients
by: L Hess, et al.
Published: (2011-05-01)

The Association between Statin Use and Reduced Migraine Likelihood: A Comprehensive Analysis of Migraine Subtypes and Statin Types in a Nationwide Korean Cohort
by: Ho Suk Kang, et al.
Published: (2024-08-01)

Biochemical, structural and clinical analysis of statins’ pleiotropic effects
by: A. N. Britov, et al.
Published: (2009-10-01)

The treatment of cholesterol: issues, effects and targets
by: James A. Ker
Published: (2010-12-01)

Guideline recommended statin eligibility and use among U.S. adults ages 20 to 39 years
by: Shoa L. Clarke, et al.
Published: (2024-12-01)

Studying the Possibility of Optimizing the Statin Therapy Algorithm in Outpatient Practice
by: D. V. Nebieridze, et al.
Published: (2020-09-01)

Assessment of lipid profile when using lipid-lowering therapy (statins) in patients with coronary atherosclerosis
by: N. E. Gavrilova, et al.
Published: (2015-11-01)

Effect of combined lipid-lowering therapy on atherosclerotic plaque vulnerability in patients with acute coronary syndrome (Combi-LLT ACS): randomized trial protocol
by: A. N. Kovalskaya, et al.
Published: (2022-12-01)

The effect of lipid-lowering therapy on lipid-related residual risk factors: a prospective study
by: Zhifan Li, et al.
Published: (2024-05-01)

Analysis of Serum Lipid Level and Drug Use in Patients with Acute Myocardial Infarction
by: LIU Chuanfen, LI Zheng, WU Manyan, CUI Yuxia, SONG Jing, ZHANG Chunying, CHEN Hong
Published: (2023-04-01)

Effects of statins beyond lipid-lowering agents in ART-treated HIV infection
by: Vikram Mehraj, et al.
Published: (2024-04-01)

Lipid-Targeted Atherosclerotic Risk Reduction in Older Adults: A Review
by: Lauren J. Hassen, et al.
Published: (2022-03-01)

Novel non‐coding RNA‐based therapeutic approaches to prevent statin‐induced liver damage
by: Claudia Bang, et al.
Published: (2012-08-01)

Comparative Efficacy and Safety of Statin Monotherapy and Statin plus Ezetimibe Combination in a Real-World Setting
by: Marat V. Ezhov, et al.
Published: (2023-11-01)

PCSK9 Inhibitor Therapy as an Alternative for Statin Intolerance
by: K. O. Shnaider, et al.
Published: (2023-12-01)

Statins—Beyond Their Use in Hypercholesterolemia: Focus on the Pediatric Population
by: Elena Lia Spoiala, et al.
Published: (2024-01-01)

Is it possible to regress atherosclerotic lesions with long-term treatment with lipoprotein apheresis?
by: Ulrich Julius, et al.
Published: (2024-10-01)

Disputable questions of statins antitumor effects in hemoblastoses
by: R. N. Mustafin
Published: (2022-07-01)

Statin therapy and atherosclerosis regression
by: A. V. Susekov
Published: (1970-01-01)

Clinical efficacy and safety outcomes of bempedoic acid: An updated systematic review and meta-analysis after CLEAR Outcomes trial
by: Amit Bhandari, et al.
Published: (2023-12-01)

Lipoprotein Metabolism, Dyslipidemia, and Lipid-Lowering Therapy in Women: A Comprehensive Review
by: Jakub Michal Zimodro, et al.
Published: (2024-07-01)

STATIN ADVERSE EFFECTS: MECHANISMS, DIAGNOSIS, PREVENTION AND MANAGEMENT
by: A. I. Dyadyk, et al.
Published: (2018-08-01)

The effects of statins on the function and differentiation of blood cells
by: Sajjad Chamani, et al.
Published: (2022-12-01)

European and US Guideline‐Based Statin Eligibility, Genetically Predicted Coronary Artery Disease, and the Risk of Major Coronary Events
by: Hanjin Park, et al.
Published: (2024-05-01)

Patterns and gaps in guideline-directed statin use for atherosclerotic cardiovascular disease by race and ethnicity
by: Ashish Sarraju, et al.
Published: (2024-03-01)