Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma

Cholangiocarcinoma (CCA) is an adenocarcinoma originating from the epithelial cells of the bile ducts/hepatocytes or peribiliary glands. There are three types of cholangiocarcinoma: intrahepatic, perihilar and distal. CCA represents approximately 3% of the gastrointestinal malignancies. The incidenc...

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Main Authors: Roxana-Luiza Caragut, Madalina Ilie, Teodor Cabel, Deniz Günșahin, Afrodita Panaitescu, Christopher Pavel, Oana Mihaela Plotogea, Ecaterina Mihaela Rînja, Gabriel Constantinescu, Vasile Sandru
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/14/5/490
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author Roxana-Luiza Caragut
Madalina Ilie
Teodor Cabel
Deniz Günșahin
Afrodita Panaitescu
Christopher Pavel
Oana Mihaela Plotogea
Ecaterina Mihaela Rînja
Gabriel Constantinescu
Vasile Sandru
author_facet Roxana-Luiza Caragut
Madalina Ilie
Teodor Cabel
Deniz Günșahin
Afrodita Panaitescu
Christopher Pavel
Oana Mihaela Plotogea
Ecaterina Mihaela Rînja
Gabriel Constantinescu
Vasile Sandru
author_sort Roxana-Luiza Caragut
collection DOAJ
description Cholangiocarcinoma (CCA) is an adenocarcinoma originating from the epithelial cells of the bile ducts/hepatocytes or peribiliary glands. There are three types of cholangiocarcinoma: intrahepatic, perihilar and distal. CCA represents approximately 3% of the gastrointestinal malignancies. The incidence of CCA is higher in regions of the Eastern world compared to the Western countries. There are multiple risk factors associated with cholangiocarcinoma such as liver fluke, primary sclerosing cholangitis, chronic hepatitis B, liver cirrhosis and non-alcoholic fatty liver disease. Endoscopy plays an important role in the diagnosis and management of cholangiocarcinoma. The main endoscopic methods used for diagnosis, biliary drainage and delivering intrabiliary local therapies are endoscopic retrograde cholangiopancreatography and endoscopic ultrasound. The purpose of this review is to analyze the current data found in literature about cholangiocarcinoma, with a focus on the actual diagnostic tools and endoscopic management options.
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spelling doaj.art-78c0d0bb740a497384e54c64879acdd02024-03-12T16:41:56ZengMDPI AGDiagnostics2075-44182024-02-0114549010.3390/diagnostics14050490Updates in Diagnosis and Endoscopic Management of CholangiocarcinomaRoxana-Luiza Caragut0Madalina Ilie1Teodor Cabel2Deniz Günșahin3Afrodita Panaitescu4Christopher Pavel5Oana Mihaela Plotogea6Ecaterina Mihaela Rînja7Gabriel Constantinescu8Vasile Sandru9Clinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaCholangiocarcinoma (CCA) is an adenocarcinoma originating from the epithelial cells of the bile ducts/hepatocytes or peribiliary glands. There are three types of cholangiocarcinoma: intrahepatic, perihilar and distal. CCA represents approximately 3% of the gastrointestinal malignancies. The incidence of CCA is higher in regions of the Eastern world compared to the Western countries. There are multiple risk factors associated with cholangiocarcinoma such as liver fluke, primary sclerosing cholangitis, chronic hepatitis B, liver cirrhosis and non-alcoholic fatty liver disease. Endoscopy plays an important role in the diagnosis and management of cholangiocarcinoma. The main endoscopic methods used for diagnosis, biliary drainage and delivering intrabiliary local therapies are endoscopic retrograde cholangiopancreatography and endoscopic ultrasound. The purpose of this review is to analyze the current data found in literature about cholangiocarcinoma, with a focus on the actual diagnostic tools and endoscopic management options.https://www.mdpi.com/2075-4418/14/5/490cholangiocarcinomadiagnosisendoscopybiliary drainagedigestive oncologyendoscopic retrograde cholangiopancreatography
spellingShingle Roxana-Luiza Caragut
Madalina Ilie
Teodor Cabel
Deniz Günșahin
Afrodita Panaitescu
Christopher Pavel
Oana Mihaela Plotogea
Ecaterina Mihaela Rînja
Gabriel Constantinescu
Vasile Sandru
Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma
Diagnostics
cholangiocarcinoma
diagnosis
endoscopy
biliary drainage
digestive oncology
endoscopic retrograde cholangiopancreatography
title Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma
title_full Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma
title_fullStr Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma
title_full_unstemmed Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma
title_short Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma
title_sort updates in diagnosis and endoscopic management of cholangiocarcinoma
topic cholangiocarcinoma
diagnosis
endoscopy
biliary drainage
digestive oncology
endoscopic retrograde cholangiopancreatography
url https://www.mdpi.com/2075-4418/14/5/490
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