Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma
Cholangiocarcinoma (CCA) is an adenocarcinoma originating from the epithelial cells of the bile ducts/hepatocytes or peribiliary glands. There are three types of cholangiocarcinoma: intrahepatic, perihilar and distal. CCA represents approximately 3% of the gastrointestinal malignancies. The incidenc...
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MDPI AG
2024-02-01
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Online Access: | https://www.mdpi.com/2075-4418/14/5/490 |
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author | Roxana-Luiza Caragut Madalina Ilie Teodor Cabel Deniz Günșahin Afrodita Panaitescu Christopher Pavel Oana Mihaela Plotogea Ecaterina Mihaela Rînja Gabriel Constantinescu Vasile Sandru |
author_facet | Roxana-Luiza Caragut Madalina Ilie Teodor Cabel Deniz Günșahin Afrodita Panaitescu Christopher Pavel Oana Mihaela Plotogea Ecaterina Mihaela Rînja Gabriel Constantinescu Vasile Sandru |
author_sort | Roxana-Luiza Caragut |
collection | DOAJ |
description | Cholangiocarcinoma (CCA) is an adenocarcinoma originating from the epithelial cells of the bile ducts/hepatocytes or peribiliary glands. There are three types of cholangiocarcinoma: intrahepatic, perihilar and distal. CCA represents approximately 3% of the gastrointestinal malignancies. The incidence of CCA is higher in regions of the Eastern world compared to the Western countries. There are multiple risk factors associated with cholangiocarcinoma such as liver fluke, primary sclerosing cholangitis, chronic hepatitis B, liver cirrhosis and non-alcoholic fatty liver disease. Endoscopy plays an important role in the diagnosis and management of cholangiocarcinoma. The main endoscopic methods used for diagnosis, biliary drainage and delivering intrabiliary local therapies are endoscopic retrograde cholangiopancreatography and endoscopic ultrasound. The purpose of this review is to analyze the current data found in literature about cholangiocarcinoma, with a focus on the actual diagnostic tools and endoscopic management options. |
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format | Article |
id | doaj.art-78c0d0bb740a497384e54c64879acdd0 |
institution | Directory Open Access Journal |
issn | 2075-4418 |
language | English |
last_indexed | 2024-04-25T00:32:16Z |
publishDate | 2024-02-01 |
publisher | MDPI AG |
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series | Diagnostics |
spelling | doaj.art-78c0d0bb740a497384e54c64879acdd02024-03-12T16:41:56ZengMDPI AGDiagnostics2075-44182024-02-0114549010.3390/diagnostics14050490Updates in Diagnosis and Endoscopic Management of CholangiocarcinomaRoxana-Luiza Caragut0Madalina Ilie1Teodor Cabel2Deniz Günșahin3Afrodita Panaitescu4Christopher Pavel5Oana Mihaela Plotogea6Ecaterina Mihaela Rînja7Gabriel Constantinescu8Vasile Sandru9Clinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaClinical Department of Gastroenterology, Bucharest Emergency Clinical Hospital, 014461 Bucharest, RomaniaCholangiocarcinoma (CCA) is an adenocarcinoma originating from the epithelial cells of the bile ducts/hepatocytes or peribiliary glands. There are three types of cholangiocarcinoma: intrahepatic, perihilar and distal. CCA represents approximately 3% of the gastrointestinal malignancies. The incidence of CCA is higher in regions of the Eastern world compared to the Western countries. There are multiple risk factors associated with cholangiocarcinoma such as liver fluke, primary sclerosing cholangitis, chronic hepatitis B, liver cirrhosis and non-alcoholic fatty liver disease. Endoscopy plays an important role in the diagnosis and management of cholangiocarcinoma. The main endoscopic methods used for diagnosis, biliary drainage and delivering intrabiliary local therapies are endoscopic retrograde cholangiopancreatography and endoscopic ultrasound. The purpose of this review is to analyze the current data found in literature about cholangiocarcinoma, with a focus on the actual diagnostic tools and endoscopic management options.https://www.mdpi.com/2075-4418/14/5/490cholangiocarcinomadiagnosisendoscopybiliary drainagedigestive oncologyendoscopic retrograde cholangiopancreatography |
spellingShingle | Roxana-Luiza Caragut Madalina Ilie Teodor Cabel Deniz Günșahin Afrodita Panaitescu Christopher Pavel Oana Mihaela Plotogea Ecaterina Mihaela Rînja Gabriel Constantinescu Vasile Sandru Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma Diagnostics cholangiocarcinoma diagnosis endoscopy biliary drainage digestive oncology endoscopic retrograde cholangiopancreatography |
title | Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma |
title_full | Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma |
title_fullStr | Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma |
title_full_unstemmed | Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma |
title_short | Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma |
title_sort | updates in diagnosis and endoscopic management of cholangiocarcinoma |
topic | cholangiocarcinoma diagnosis endoscopy biliary drainage digestive oncology endoscopic retrograde cholangiopancreatography |
url | https://www.mdpi.com/2075-4418/14/5/490 |
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