Automatic data-driven design and 3D printing of custom ocular prostheses

Abstract Millions of people require custom ocular prostheses due to eye loss or congenital defects. The current fully manual manufacturing processes used by highly skilled ocularists are time-consuming with varying quality. Additive manufacturing technology has the potential to simplify the manufact...

Full description

Bibliographic Details
Main Authors: Johann Reinhard, Philipp Urban, Stephen Bell, David Carpenter, Mandeep S. Sagoo
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45345-5
_version_ 1827326867038797824
author Johann Reinhard
Philipp Urban
Stephen Bell
David Carpenter
Mandeep S. Sagoo
author_facet Johann Reinhard
Philipp Urban
Stephen Bell
David Carpenter
Mandeep S. Sagoo
author_sort Johann Reinhard
collection DOAJ
description Abstract Millions of people require custom ocular prostheses due to eye loss or congenital defects. The current fully manual manufacturing processes used by highly skilled ocularists are time-consuming with varying quality. Additive manufacturing technology has the potential to simplify the manufacture of ocular prosthetics, but existing approaches just replace to various degrees craftsmanship by manual digital design and still require substantial expertise and time. Here we present an automatic digital end-to-end process for producing custom ocular prostheses that uses image data from an anterior segment optical coherence tomography device and considers both shape and appearance. Our approach uses a statistical shape model to predict, based on incomplete surface information of the eye socket, a best fitting prosthesis shape. We use a colour characterized image of the healthy fellow eye to determine and procedurally generate the prosthesis’s appearance that matches the fellow eye. The prosthesis is manufactured using a multi-material full-colour 3D printer and postprocessed to satisfy regulatory compliance. We demonstrate the effectiveness of our approach by presenting results for 10 clinic patients who received a 3D printed prosthesis. Compared to a current manual process, our approach requires five times less labour of the ocularist and produces reproducible output.
first_indexed 2024-03-07T14:51:35Z
format Article
id doaj.art-78c550ebba854eda905c5a50d6ed79db
institution Directory Open Access Journal
issn 2041-1723
language English
last_indexed 2024-03-07T14:51:35Z
publishDate 2024-02-01
publisher Nature Portfolio
record_format Article
series Nature Communications
spelling doaj.art-78c550ebba854eda905c5a50d6ed79db2024-03-05T19:38:40ZengNature PortfolioNature Communications2041-17232024-02-0115111410.1038/s41467-024-45345-5Automatic data-driven design and 3D printing of custom ocular prosthesesJohann Reinhard0Philipp Urban1Stephen Bell2David Carpenter3Mandeep S. Sagoo4Fraunhofer Institute for Computer Graphics Research IGDFraunhofer Institute for Computer Graphics Research IGDOcupeye Ltd.Ocular Prosthetics Department, Moorfields Eye Hospital NHS Foundation TrustNIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and UCL Institute of OphthalmologyAbstract Millions of people require custom ocular prostheses due to eye loss or congenital defects. The current fully manual manufacturing processes used by highly skilled ocularists are time-consuming with varying quality. Additive manufacturing technology has the potential to simplify the manufacture of ocular prosthetics, but existing approaches just replace to various degrees craftsmanship by manual digital design and still require substantial expertise and time. Here we present an automatic digital end-to-end process for producing custom ocular prostheses that uses image data from an anterior segment optical coherence tomography device and considers both shape and appearance. Our approach uses a statistical shape model to predict, based on incomplete surface information of the eye socket, a best fitting prosthesis shape. We use a colour characterized image of the healthy fellow eye to determine and procedurally generate the prosthesis’s appearance that matches the fellow eye. The prosthesis is manufactured using a multi-material full-colour 3D printer and postprocessed to satisfy regulatory compliance. We demonstrate the effectiveness of our approach by presenting results for 10 clinic patients who received a 3D printed prosthesis. Compared to a current manual process, our approach requires five times less labour of the ocularist and produces reproducible output.https://doi.org/10.1038/s41467-024-45345-5
spellingShingle Johann Reinhard
Philipp Urban
Stephen Bell
David Carpenter
Mandeep S. Sagoo
Automatic data-driven design and 3D printing of custom ocular prostheses
Nature Communications
title Automatic data-driven design and 3D printing of custom ocular prostheses
title_full Automatic data-driven design and 3D printing of custom ocular prostheses
title_fullStr Automatic data-driven design and 3D printing of custom ocular prostheses
title_full_unstemmed Automatic data-driven design and 3D printing of custom ocular prostheses
title_short Automatic data-driven design and 3D printing of custom ocular prostheses
title_sort automatic data driven design and 3d printing of custom ocular prostheses
url https://doi.org/10.1038/s41467-024-45345-5
work_keys_str_mv AT johannreinhard automaticdatadrivendesignand3dprintingofcustomocularprostheses
AT philippurban automaticdatadrivendesignand3dprintingofcustomocularprostheses
AT stephenbell automaticdatadrivendesignand3dprintingofcustomocularprostheses
AT davidcarpenter automaticdatadrivendesignand3dprintingofcustomocularprostheses
AT mandeepssagoo automaticdatadrivendesignand3dprintingofcustomocularprostheses