Correlation between dyslipidemia and severity of allergic rhinitis

Abstract Background Allergic rhinitis is a common problem affecting between 20 and 25% of the population lowering the quality of life (QOL) more than any other disease. Dyslipidemia is known to impact potently the development of atopy as it promotes proatopic Th2 immunity and allergic inflammation....

Full description

Bibliographic Details
Main Authors: Mohamed R. Ahmed, Yasser T. Madian, Mohammed T. El-Tabbakh, Ahmed T. El-Serafi, Gamela M. Nasr, Waheed F. Hessam
Format: Article
Language:English
Published: SpringerOpen 2018-05-01
Series:The Egyptian Journal of Otolaryngology
Subjects:
Online Access:http://link.springer.com/article/10.4103/ejo.ejo_90_17
_version_ 1797203785446064128
author Mohamed R. Ahmed
Yasser T. Madian
Mohammed T. El-Tabbakh
Ahmed T. El-Serafi
Gamela M. Nasr
Waheed F. Hessam
author_facet Mohamed R. Ahmed
Yasser T. Madian
Mohammed T. El-Tabbakh
Ahmed T. El-Serafi
Gamela M. Nasr
Waheed F. Hessam
author_sort Mohamed R. Ahmed
collection DOAJ
description Abstract Background Allergic rhinitis is a common problem affecting between 20 and 25% of the population lowering the quality of life (QOL) more than any other disease. Dyslipidemia is known to impact potently the development of atopy as it promotes proatopic Th2 immunity and allergic inflammation. Objective The aim was to test the correlation between severity of allergic rhinitis and dyslipidemia. Materials and methods A comparative study carried out on 350 allergic rhinitis patients were subjected to full serum lipid assays, visual analog scale assessing their nasal symptoms, and QOL assessment using a seven-point scale. Results Patients were divided into two groups (according to their lipid profile): abnormal dyslipidemia group (33%) and normal lipid profile group (67%). The abnormal dyslipidemia group showed a more intense allergic rhinitis symptoms compared with the normal lipid profile with poor QOL score (1.97). Conclusion Dyslipidemia might play an important role in increasing the severity of allergic rhinitis symptoms with impaired patients’ QOL; therefore, its control could achieve better treatment outcomes.
first_indexed 2024-04-24T08:24:51Z
format Article
id doaj.art-78c55e463b8b4aeea4801ff74fd48062
institution Directory Open Access Journal
issn 1012-5574
2090-8539
language English
last_indexed 2024-04-24T08:24:51Z
publishDate 2018-05-01
publisher SpringerOpen
record_format Article
series The Egyptian Journal of Otolaryngology
spelling doaj.art-78c55e463b8b4aeea4801ff74fd480622024-04-16T23:07:00ZengSpringerOpenThe Egyptian Journal of Otolaryngology1012-55742090-85392018-05-0134211111510.4103/ejo.ejo_90_17Correlation between dyslipidemia and severity of allergic rhinitisMohamed R. Ahmed0Yasser T. Madian1Mohammed T. El-Tabbakh2Ahmed T. El-Serafi3Gamela M. Nasr4Waheed F. Hessam5Otolaryngology Unit, Faculty of Medicine, Suez Canal UniversityOtolaryngology Unit, Faculty of Medicine, Suez Canal UniversityOtolaryngology Unit, Faculty of Medicine, Suez Canal UniversityMedical Biochemistry Units, Suez Canal UniversityCardiology Units, Suez Canal UniversityDepartments of Microbiology and Immunology, Faculty of Medicine, Suez Canal UniversityAbstract Background Allergic rhinitis is a common problem affecting between 20 and 25% of the population lowering the quality of life (QOL) more than any other disease. Dyslipidemia is known to impact potently the development of atopy as it promotes proatopic Th2 immunity and allergic inflammation. Objective The aim was to test the correlation between severity of allergic rhinitis and dyslipidemia. Materials and methods A comparative study carried out on 350 allergic rhinitis patients were subjected to full serum lipid assays, visual analog scale assessing their nasal symptoms, and QOL assessment using a seven-point scale. Results Patients were divided into two groups (according to their lipid profile): abnormal dyslipidemia group (33%) and normal lipid profile group (67%). The abnormal dyslipidemia group showed a more intense allergic rhinitis symptoms compared with the normal lipid profile with poor QOL score (1.97). Conclusion Dyslipidemia might play an important role in increasing the severity of allergic rhinitis symptoms with impaired patients’ QOL; therefore, its control could achieve better treatment outcomes.http://link.springer.com/article/10.4103/ejo.ejo_90_17allergylipidquality of liferhinitis
spellingShingle Mohamed R. Ahmed
Yasser T. Madian
Mohammed T. El-Tabbakh
Ahmed T. El-Serafi
Gamela M. Nasr
Waheed F. Hessam
Correlation between dyslipidemia and severity of allergic rhinitis
The Egyptian Journal of Otolaryngology
allergy
lipid
quality of life
rhinitis
title Correlation between dyslipidemia and severity of allergic rhinitis
title_full Correlation between dyslipidemia and severity of allergic rhinitis
title_fullStr Correlation between dyslipidemia and severity of allergic rhinitis
title_full_unstemmed Correlation between dyslipidemia and severity of allergic rhinitis
title_short Correlation between dyslipidemia and severity of allergic rhinitis
title_sort correlation between dyslipidemia and severity of allergic rhinitis
topic allergy
lipid
quality of life
rhinitis
url http://link.springer.com/article/10.4103/ejo.ejo_90_17
work_keys_str_mv AT mohamedrahmed correlationbetweendyslipidemiaandseverityofallergicrhinitis
AT yassertmadian correlationbetweendyslipidemiaandseverityofallergicrhinitis
AT mohammedteltabbakh correlationbetweendyslipidemiaandseverityofallergicrhinitis
AT ahmedtelserafi correlationbetweendyslipidemiaandseverityofallergicrhinitis
AT gamelamnasr correlationbetweendyslipidemiaandseverityofallergicrhinitis
AT waheedfhessam correlationbetweendyslipidemiaandseverityofallergicrhinitis