Multi-phosphorylation reaction and clustering tune Pom1 gradient mid-cell levels according to cell size

Protein concentration gradients pattern developing organisms and single cells. In Schizosaccharomyces pombe rod-shaped cells, Pom1 kinase forms gradients with maxima at cell poles. Pom1 controls the timing of mitotic entry by inhibiting Cdr2, which forms stable membrane-associated nodes at mid-cell....

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Bibliographic Details
Main Authors: Veneta Gerganova, Charlotte Floderer, Anna Archetti, Laetitia Michon, Lina Carlini, Thais Reichler, Suliana Manley, Sophie G Martin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-05-01
Series:eLife
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Online Access:https://elifesciences.org/articles/45983

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