Multi-phosphorylation reaction and clustering tune Pom1 gradient mid-cell levels according to cell size
Protein concentration gradients pattern developing organisms and single cells. In Schizosaccharomyces pombe rod-shaped cells, Pom1 kinase forms gradients with maxima at cell poles. Pom1 controls the timing of mitotic entry by inhibiting Cdr2, which forms stable membrane-associated nodes at mid-cell....
Main Authors: | Veneta Gerganova, Charlotte Floderer, Anna Archetti, Laetitia Michon, Lina Carlini, Thais Reichler, Suliana Manley, Sophie G Martin |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2019-05-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/45983 |
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