Identification of Aryl Polyamines Derivatives as Anti-<i>Trypanosoma cruzi</i> Agents Targeting Iron Superoxide Dismutase

Identification of Aryl Polyamines Derivatives as Anti-<i>Trypanosoma cruzi</i> Agents Targeting Iron Superoxide Dismutase

Chagas disease (CD) is a tropical and potentially fatal infection caused by <i>Trypanosoma cruzi</i>. Although CD was limited to Latin America as a silent disease, CD has become widespread as a result of globalization. Currently, 6–8 million people are infected worldwide, and no effectiv...

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Main Authors: Rubén Martín-Escolano, Daniel Molina-Carreño, Javier Martín-Escolano, Mª Paz Clares, Cristina Galiana-Roselló, Jorge González-García, Nuria Cirauqui, José M. Llinares, María José Rosales, Enrique García-España, Clotilde Marín
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Pharmaceutics
Subjects:
chagas disease
chemotherapy
drug discovery
aryl polyamines
<i>Trypanosoma cruzi</i>
Online Access:https://www.mdpi.com/1999-4923/15/1/140

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