MAIT cells altered phenotype and cytotoxicity in lupus patients are linked to renal disease severity and outcome

MAIT cells altered phenotype and cytotoxicity in lupus patients are linked to renal disease severity and outcome

IntroductionSystemic lupus erythematosus (SLE) is an autoimmune disease in which circulating immune complexes can cause different types of glomerulonephritis, according to immune deposits and to the type of glomerular cell injury. Proliferative lesions represent the most severe form of lupus nephrit...

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Main Authors: Elena Litvinova, Carine Bounaix, Guillaume Hanouna, Jennifer Da Silva, Laura Noailles, Lucie Beaudoin, Michael Padden, Nessrine Bellamri, Agnès Lehuen, Eric Daugas, Renato C. Monteiro, Héloïse Flament
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
MAIT cell
lupus nephritis
granzyme B
activation
prognosis markers
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1205405/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1205405/full

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