An unrecognized undifferentiated tumor of the pancreas: a case report
SMARCA4-deficient tumors are gaining attention, and this type of tumor is highly malignant with a poor prognosis. The frequency of SMARCA4 deletion varies in different tumors. However, it has never been identified in the pancreas. A 67-year-old woman presented with upper abdominal pain lasting for h...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Health/LWW
2023-12-01
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| Series: | Journal of Pancreatology |
| Online Access: | http://journals.lww.com/10.1097/JP9.0000000000000132 |
| _version_ | 1797374979764912128 |
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| author | Chaoyu Pang Zhiyao Fan Peng Su Hanxiang Zhan |
| author_facet | Chaoyu Pang Zhiyao Fan Peng Su Hanxiang Zhan |
| author_sort | Chaoyu Pang |
| collection | DOAJ |
| description | SMARCA4-deficient tumors are gaining attention, and this type of tumor is highly malignant with a poor prognosis. The frequency of SMARCA4 deletion varies in different tumors. However, it has never been identified in the pancreas. A 67-year-old woman presented with upper abdominal pain lasting for half a month. Computed tomography indicated a space-occupying lesion in the head of the pancreas, considered a malignant tumor. Further Endoscopic ultrasound fine-needle aspiration was performed and reported as SMARCA4-deficient undifferentiated pancreatic tumor. The patient received no treatment and survived only two and a half months from diagnosis to death. We are the first to report SMARCA4-deficient pancreatic undifferentiated tumor in which this new tumor entity presents with poorer overall survival. We also summarized the advances of SMARCA4 in oncology and treatment. |
| first_indexed | 2024-03-08T19:15:36Z |
| format | Article |
| id | doaj.art-78d469c45a2e4824bd4339564d3e1ec3 |
| institution | Directory Open Access Journal |
| issn | 2096-5664 |
| language | English |
| last_indexed | 2024-03-08T19:15:36Z |
| publishDate | 2023-12-01 |
| publisher | Wolters Kluwer Health/LWW |
| record_format | Article |
| series | Journal of Pancreatology |
| spelling | doaj.art-78d469c45a2e4824bd4339564d3e1ec32023-12-27T06:52:13ZengWolters Kluwer Health/LWWJournal of Pancreatology2096-56642023-12-016422522710.1097/JP9.0000000000000132202312000-00010An unrecognized undifferentiated tumor of the pancreas: a case reportChaoyu Pang0Zhiyao Fan1Peng Su2Hanxiang Zhan3a Division of Pancreatic Surgery, Department of General Surgery, Qilu Hospital, Shandong University, Jinan 250012, Chinaa Division of Pancreatic Surgery, Department of General Surgery, Qilu Hospital, Shandong University, Jinan 250012, Chinab Department of Pathology, Qilu Hospital, Shandong University, Jinan 250012, Chinaa Division of Pancreatic Surgery, Department of General Surgery, Qilu Hospital, Shandong University, Jinan 250012, ChinaSMARCA4-deficient tumors are gaining attention, and this type of tumor is highly malignant with a poor prognosis. The frequency of SMARCA4 deletion varies in different tumors. However, it has never been identified in the pancreas. A 67-year-old woman presented with upper abdominal pain lasting for half a month. Computed tomography indicated a space-occupying lesion in the head of the pancreas, considered a malignant tumor. Further Endoscopic ultrasound fine-needle aspiration was performed and reported as SMARCA4-deficient undifferentiated pancreatic tumor. The patient received no treatment and survived only two and a half months from diagnosis to death. We are the first to report SMARCA4-deficient pancreatic undifferentiated tumor in which this new tumor entity presents with poorer overall survival. We also summarized the advances of SMARCA4 in oncology and treatment.http://journals.lww.com/10.1097/JP9.0000000000000132 |
| spellingShingle | Chaoyu Pang Zhiyao Fan Peng Su Hanxiang Zhan An unrecognized undifferentiated tumor of the pancreas: a case report Journal of Pancreatology |
| title | An unrecognized undifferentiated tumor of the pancreas: a case report |
| title_full | An unrecognized undifferentiated tumor of the pancreas: a case report |
| title_fullStr | An unrecognized undifferentiated tumor of the pancreas: a case report |
| title_full_unstemmed | An unrecognized undifferentiated tumor of the pancreas: a case report |
| title_short | An unrecognized undifferentiated tumor of the pancreas: a case report |
| title_sort | unrecognized undifferentiated tumor of the pancreas a case report |
| url | http://journals.lww.com/10.1097/JP9.0000000000000132 |
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