The role of oxidised self-lipids and alveolar macrophage CD1b expression in COPD

The role of oxidised self-lipids and alveolar macrophage CD1b expression in COPD

Abstract In chronic obstructive pulmonary disease (COPD) apoptotic bronchial epithelial cells are increased, and their phagocytosis by alveolar macrophages (AM) is decreased alongside bacterial phagocytosis. Epithelial cellular lipids, including those exposed on uncleared apoptotic bodies, can becom...

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Bibliographic Details
Main Authors: Miranda P. Ween, Jake B. White, Hai B. Tran, Violet Mukaro, Charles Jones, Matthew Macowan, Gregory Hodge, Paul J. Trim, Marten F. Snel, Sandra J. Hodge
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82481-0

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