Nickamine: A General Catalyst for Cross Coupling of Alkyl Halides and Direct Alkylation

A nickel pincer complex, Nickamine, is shown to be an active catalyst for a large number of reactions including cross coupling of non-activated alkyl halides and direct C–H alkylation of alkynes and aromatic heterocycles. This work was rewarded by the 2011 Werner Prize from the Swiss Chemic...

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Main Author: Xile Hu
Format: Article
Language:deu
Published: Swiss Chemical Society 2012-04-01
Series:CHIMIA
Subjects:
Online Access:https://www.chimia.ch/chimia/article/view/5179
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author Xile Hu
author_facet Xile Hu
author_sort Xile Hu
collection DOAJ
description A nickel pincer complex, Nickamine, is shown to be an active catalyst for a large number of reactions including cross coupling of non-activated alkyl halides and direct C–H alkylation of alkynes and aromatic heterocycles. This work was rewarded by the 2011 Werner Prize from the Swiss Chemical Society.
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spelling doaj.art-78e08117f2534a80ab907e917344b05d2022-12-21T17:24:52ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24242012-04-0166410.2533/chimia.2012.154Nickamine: A General Catalyst for Cross Coupling of Alkyl Halides and Direct AlkylationXile Hu0Werner Prize winner 2011, Ecole Polytechnique Fédérale de Lausanne Institute of Chemical Sciences and Engineering EPFL-ISIC-LSCI CH-1015 Lausanne, Switzerland. xile.hu@epfl.ch A nickel pincer complex, Nickamine, is shown to be an active catalyst for a large number of reactions including cross coupling of non-activated alkyl halides and direct C–H alkylation of alkynes and aromatic heterocycles. This work was rewarded by the 2011 Werner Prize from the Swiss Chemical Society. https://www.chimia.ch/chimia/article/view/5179C–h functionalizationCross couplingHomogeneous catalysisOrganometallic chemistryNickel
spellingShingle Xile Hu
Nickamine: A General Catalyst for Cross Coupling of Alkyl Halides and Direct Alkylation
CHIMIA
C–h functionalization
Cross coupling
Homogeneous catalysis
Organometallic chemistry
Nickel
title Nickamine: A General Catalyst for Cross Coupling of Alkyl Halides and Direct Alkylation
title_full Nickamine: A General Catalyst for Cross Coupling of Alkyl Halides and Direct Alkylation
title_fullStr Nickamine: A General Catalyst for Cross Coupling of Alkyl Halides and Direct Alkylation
title_full_unstemmed Nickamine: A General Catalyst for Cross Coupling of Alkyl Halides and Direct Alkylation
title_short Nickamine: A General Catalyst for Cross Coupling of Alkyl Halides and Direct Alkylation
title_sort nickamine a general catalyst for cross coupling of alkyl halides and direct alkylation
topic C–h functionalization
Cross coupling
Homogeneous catalysis
Organometallic chemistry
Nickel
url https://www.chimia.ch/chimia/article/view/5179
work_keys_str_mv AT xilehu nickamineageneralcatalystforcrosscouplingofalkylhalidesanddirectalkylation