Effect of pretreatment with matrix metalloproteinase inhibitors on the durability of bond strength of fiber posts to radicular dentin
Abstract Objectives Application of matrix metalloproteinases inhibitors has been suggested to improve the durability of resin–dentin bonding. The purpose of this study was to evaluate the effect of dimethyl sulfoxide (DMSO), carbodiimide (EDC), and chlorhexidine (CHX) treatment on the push‐out bond...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-08-01
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| Series: | Clinical and Experimental Dental Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cre2.569 |
| _version_ | 1811321215788253184 |
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| author | Kiamehr Ghazvehi Aida Saffarpour Sareh Habibzadeh |
| author_facet | Kiamehr Ghazvehi Aida Saffarpour Sareh Habibzadeh |
| author_sort | Kiamehr Ghazvehi |
| collection | DOAJ |
| description | Abstract Objectives Application of matrix metalloproteinases inhibitors has been suggested to improve the durability of resin–dentin bonding. The purpose of this study was to evaluate the effect of dimethyl sulfoxide (DMSO), carbodiimide (EDC), and chlorhexidine (CHX) treatment on the push‐out bond strength of fiber posts to radicular dentin. Materials and Methods 24 extracted premolars were assigned randomly to 4 groups after root canal treatment and post space preparation (n = 6). In the first, second, and third groups, radicular dentin was treated with 1 ml of 5% DMSO, 0.3 M EDC, and 2% CHX, respectively. The fourth group (control) received no treatment. The root canals were primed with ED primer II, and the fiber posts were cemented with Panavia F2.0. In each group, half of the specimens were subjected to the push‐out test and the other half to 3000 thermal cycles before testing. Data were analyzed using two‐way analysis of variance via SPSS version 20 (p < .05). Results Among the nonthermocycled specimens, the values of push‐out bond strength were observed in the control, EDC, CHX, and DMSO groups, in decreasing order. Among the thermocycled specimens, the values were observed in the control, EDC, DMSO, and CHX groups in decreasing order. Thermocycling had a significant adverse effect on the push‐out bond strength (p = .015), but the effect of material (p = .375), and the interaction effect of material and thermocycling (p = .998) were not significant. Conclusions Application of CHX, DMSO, and EDC had no significant effect on the bond strength of fiber posts to radicular dentin. |
| first_indexed | 2024-04-13T13:14:05Z |
| format | Article |
| id | doaj.art-78e288827b1d4fb89bcd95cc0cd5c360 |
| institution | Directory Open Access Journal |
| issn | 2057-4347 |
| language | English |
| last_indexed | 2024-04-13T13:14:05Z |
| publishDate | 2022-08-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Experimental Dental Research |
| spelling | doaj.art-78e288827b1d4fb89bcd95cc0cd5c3602022-12-22T02:45:32ZengWileyClinical and Experimental Dental Research2057-43472022-08-018489389910.1002/cre2.569Effect of pretreatment with matrix metalloproteinase inhibitors on the durability of bond strength of fiber posts to radicular dentinKiamehr Ghazvehi0Aida Saffarpour1Sareh Habibzadeh2Department of Prosthodontics, School of Dentistry, International Campus Tehran University of Medical Sciences Tehran IranDental Research Center, Dentistry Research Institute Tehran University of Medical Sciences Tehran IranDepartment of Prosthodontics, School of Dentistry, International Campus Tehran University of Medical Sciences Tehran IranAbstract Objectives Application of matrix metalloproteinases inhibitors has been suggested to improve the durability of resin–dentin bonding. The purpose of this study was to evaluate the effect of dimethyl sulfoxide (DMSO), carbodiimide (EDC), and chlorhexidine (CHX) treatment on the push‐out bond strength of fiber posts to radicular dentin. Materials and Methods 24 extracted premolars were assigned randomly to 4 groups after root canal treatment and post space preparation (n = 6). In the first, second, and third groups, radicular dentin was treated with 1 ml of 5% DMSO, 0.3 M EDC, and 2% CHX, respectively. The fourth group (control) received no treatment. The root canals were primed with ED primer II, and the fiber posts were cemented with Panavia F2.0. In each group, half of the specimens were subjected to the push‐out test and the other half to 3000 thermal cycles before testing. Data were analyzed using two‐way analysis of variance via SPSS version 20 (p < .05). Results Among the nonthermocycled specimens, the values of push‐out bond strength were observed in the control, EDC, CHX, and DMSO groups, in decreasing order. Among the thermocycled specimens, the values were observed in the control, EDC, DMSO, and CHX groups in decreasing order. Thermocycling had a significant adverse effect on the push‐out bond strength (p = .015), but the effect of material (p = .375), and the interaction effect of material and thermocycling (p = .998) were not significant. Conclusions Application of CHX, DMSO, and EDC had no significant effect on the bond strength of fiber posts to radicular dentin.https://doi.org/10.1002/cre2.569chlorhexidinedimethyl sulfoxidefiber postmatrix metalloproteinase |
| spellingShingle | Kiamehr Ghazvehi Aida Saffarpour Sareh Habibzadeh Effect of pretreatment with matrix metalloproteinase inhibitors on the durability of bond strength of fiber posts to radicular dentin Clinical and Experimental Dental Research chlorhexidine dimethyl sulfoxide fiber post matrix metalloproteinase |
| title | Effect of pretreatment with matrix metalloproteinase inhibitors on the durability of bond strength of fiber posts to radicular dentin |
| title_full | Effect of pretreatment with matrix metalloproteinase inhibitors on the durability of bond strength of fiber posts to radicular dentin |
| title_fullStr | Effect of pretreatment with matrix metalloproteinase inhibitors on the durability of bond strength of fiber posts to radicular dentin |
| title_full_unstemmed | Effect of pretreatment with matrix metalloproteinase inhibitors on the durability of bond strength of fiber posts to radicular dentin |
| title_short | Effect of pretreatment with matrix metalloproteinase inhibitors on the durability of bond strength of fiber posts to radicular dentin |
| title_sort | effect of pretreatment with matrix metalloproteinase inhibitors on the durability of bond strength of fiber posts to radicular dentin |
| topic | chlorhexidine dimethyl sulfoxide fiber post matrix metalloproteinase |
| url | https://doi.org/10.1002/cre2.569 |
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