Hemoglobin A1c (Hba1c) is Strongly Correlated with Mean Corpuscular Volume Among Type 2 Diabetes Mellitus (T2dm) Patients Admitted in a Tertiary Hospital in East Java, Indonesia
Highlight: • Moderate negative significant correlation between HbA1c and MCV levels in T2DM was yet reported widely. • MCV levels could mirror health indicator in adult T2DM patients. Abstract: HbA1c showed the average level of blood sugar in the recent 2-3 months. This parameter can be used to...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Universitas Airlangga
2022-03-01
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| Series: | Folia Medica Indonesiana |
| Subjects: | |
| Online Access: | https://e-journal.unair.ac.id/FMI/article/view/32628 |
| _version_ | 1818138314370187264 |
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| author | Yusuf Salim Viskasari Pintoko Kalanjati Jongky Hendro Prajitno Rezy Ramawan Melbiarta |
| author_facet | Yusuf Salim Viskasari Pintoko Kalanjati Jongky Hendro Prajitno Rezy Ramawan Melbiarta |
| author_sort | Yusuf Salim |
| collection | DOAJ |
| description | Highlight:
• Moderate negative significant correlation between HbA1c and MCV levels in T2DM was yet reported widely.
• MCV levels could mirror health indicator in adult T2DM patients.
Abstract:
HbA1c showed the average level of blood sugar in the recent 2-3 months. This parameter can be used to help physicians to diagnose T2DM and to plan appropriate treatment. Meanwhile, the mean corpuscular volume (MCV) is established from the erythrocytes levels as one of the blood corpuscles, in which hemoglobin is bound to. We hypothesize that MCV is correlated to the HbA1c levels and could be an indicator of blood sugar levels in adult T2DM patients. A retrospective cross-sectional study based on the medical record of patients admitted to the Outpatient Section of Department of Internal Medicine, Dr. Soetomo General Academic Hospital, Indonesia from January to December 2019 was done. Patients under 18-years old, and incomplete medical record data were excluded. Adult patients diagnosed with T2DM and have been received initial treatment in this section were included (n=1.688). Data was analyzed using correlation test in SPSS 17.0 (USA), p-value less than 0.05 was considered significant. We found a significant negative correlation between HbA1c and MCV levels in these patients (r=-0.312; p<0.001). MCV levels showed a paradoxical pattern against the blood glucose levels in T2DM and could serve as the health indicator in these patients. |
| first_indexed | 2024-12-11T10:10:14Z |
| format | Article |
| id | doaj.art-78e61efd13af432f9b03067fdc4f59fc |
| institution | Directory Open Access Journal |
| issn | 2355-8393 2599-056X |
| language | English |
| last_indexed | 2024-12-11T10:10:14Z |
| publishDate | 2022-03-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Folia Medica Indonesiana |
| spelling | doaj.art-78e61efd13af432f9b03067fdc4f59fc2022-12-22T01:11:46ZengUniversitas AirlanggaFolia Medica Indonesiana2355-83932599-056X2022-03-01581464910.20473/fmi.v58i1.3262814955Hemoglobin A1c (Hba1c) is Strongly Correlated with Mean Corpuscular Volume Among Type 2 Diabetes Mellitus (T2dm) Patients Admitted in a Tertiary Hospital in East Java, IndonesiaYusuf Salim0Viskasari Pintoko Kalanjati1Jongky Hendro Prajitno2Rezy Ramawan Melbiarta3Medical Program, Faculty of Medicine, Universitas Airlangga, SurabayaDepartment of Anatomy, Histology, and Pharmacology, Faculty of Medicine, Universitas Airlangga, SurabayaEndocrine and Metabolism Division, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital SurabayaMedical Program, Faculty of Medicine, Universitas Airlangga, SurabayaHighlight: • Moderate negative significant correlation between HbA1c and MCV levels in T2DM was yet reported widely. • MCV levels could mirror health indicator in adult T2DM patients. Abstract: HbA1c showed the average level of blood sugar in the recent 2-3 months. This parameter can be used to help physicians to diagnose T2DM and to plan appropriate treatment. Meanwhile, the mean corpuscular volume (MCV) is established from the erythrocytes levels as one of the blood corpuscles, in which hemoglobin is bound to. We hypothesize that MCV is correlated to the HbA1c levels and could be an indicator of blood sugar levels in adult T2DM patients. A retrospective cross-sectional study based on the medical record of patients admitted to the Outpatient Section of Department of Internal Medicine, Dr. Soetomo General Academic Hospital, Indonesia from January to December 2019 was done. Patients under 18-years old, and incomplete medical record data were excluded. Adult patients diagnosed with T2DM and have been received initial treatment in this section were included (n=1.688). Data was analyzed using correlation test in SPSS 17.0 (USA), p-value less than 0.05 was considered significant. We found a significant negative correlation between HbA1c and MCV levels in these patients (r=-0.312; p<0.001). MCV levels showed a paradoxical pattern against the blood glucose levels in T2DM and could serve as the health indicator in these patients.https://e-journal.unair.ac.id/FMI/article/view/32628diabeteshemoglobinhba1cmcvhealth risk |
| spellingShingle | Yusuf Salim Viskasari Pintoko Kalanjati Jongky Hendro Prajitno Rezy Ramawan Melbiarta Hemoglobin A1c (Hba1c) is Strongly Correlated with Mean Corpuscular Volume Among Type 2 Diabetes Mellitus (T2dm) Patients Admitted in a Tertiary Hospital in East Java, Indonesia Folia Medica Indonesiana diabetes hemoglobin hba1c mcv health risk |
| title | Hemoglobin A1c (Hba1c) is Strongly Correlated with Mean Corpuscular Volume Among Type 2 Diabetes Mellitus (T2dm) Patients Admitted in a Tertiary Hospital in East Java, Indonesia |
| title_full | Hemoglobin A1c (Hba1c) is Strongly Correlated with Mean Corpuscular Volume Among Type 2 Diabetes Mellitus (T2dm) Patients Admitted in a Tertiary Hospital in East Java, Indonesia |
| title_fullStr | Hemoglobin A1c (Hba1c) is Strongly Correlated with Mean Corpuscular Volume Among Type 2 Diabetes Mellitus (T2dm) Patients Admitted in a Tertiary Hospital in East Java, Indonesia |
| title_full_unstemmed | Hemoglobin A1c (Hba1c) is Strongly Correlated with Mean Corpuscular Volume Among Type 2 Diabetes Mellitus (T2dm) Patients Admitted in a Tertiary Hospital in East Java, Indonesia |
| title_short | Hemoglobin A1c (Hba1c) is Strongly Correlated with Mean Corpuscular Volume Among Type 2 Diabetes Mellitus (T2dm) Patients Admitted in a Tertiary Hospital in East Java, Indonesia |
| title_sort | hemoglobin a1c hba1c is strongly correlated with mean corpuscular volume among type 2 diabetes mellitus t2dm patients admitted in a tertiary hospital in east java indonesia |
| topic | diabetes hemoglobin hba1c mcv health risk |
| url | https://e-journal.unair.ac.id/FMI/article/view/32628 |
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