Microbial Transformations of 7-Methoxyflavanone
Microbial transformations of racemic 7-methoxyflavanone using strains of the genus Aspergillus (A. niger KB, A. ochraceus 456) and the strain Penicillium chermesinum 113 were described. The strain A. niger KB catalysed carbonyl group reduction, leading to (±)-2,4-cis-7-methoxyflavan-4-o...
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-12-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/17/12/14810 |
| _version_ | 1818248474700808192 |
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| author | Edyta Kostrzewa-Susłow Tomasz Janeczko |
| author_facet | Edyta Kostrzewa-Susłow Tomasz Janeczko |
| author_sort | Edyta Kostrzewa-Susłow |
| collection | DOAJ |
| description | Microbial transformations of racemic 7-methoxyflavanone using strains of the genus Aspergillus (A. niger KB, A. ochraceus 456) and the strain Penicillium chermesinum 113 were described. The strain A. niger KB catalysed carbonyl group reduction, leading to (±)-2,4-cis-7-methoxyflavan-4-ol. Biotransformation with the help of A. ochraceus 456 gave two products: (+)-2,4-trans-7-methoxyflavan-4-ol and 4'-hydroxy-7-methoxyflavone. Transformation by means of P. chermesinum 113 resulted in a dihydrochalcone product, 4,2'-dihydroxy-4'-methoxydihydrochalcone. DPPH scavenging activity test proved that all the biotransformations products have higher antioxidant activity that the substrate. |
| first_indexed | 2024-12-12T15:21:11Z |
| format | Article |
| id | doaj.art-78e782120ac84d25aedbb1afeb217ea8 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-12T15:21:11Z |
| publishDate | 2012-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-78e782120ac84d25aedbb1afeb217ea82022-12-22T00:20:23ZengMDPI AGMolecules1420-30492012-12-011712148101482010.3390/molecules171214810Microbial Transformations of 7-MethoxyflavanoneEdyta Kostrzewa-SusłowTomasz JaneczkoMicrobial transformations of racemic 7-methoxyflavanone using strains of the genus Aspergillus (A. niger KB, A. ochraceus 456) and the strain Penicillium chermesinum 113 were described. The strain A. niger KB catalysed carbonyl group reduction, leading to (±)-2,4-cis-7-methoxyflavan-4-ol. Biotransformation with the help of A. ochraceus 456 gave two products: (+)-2,4-trans-7-methoxyflavan-4-ol and 4'-hydroxy-7-methoxyflavone. Transformation by means of P. chermesinum 113 resulted in a dihydrochalcone product, 4,2'-dihydroxy-4'-methoxydihydrochalcone. DPPH scavenging activity test proved that all the biotransformations products have higher antioxidant activity that the substrate.http://www.mdpi.com/1420-3049/17/12/14810biotransformation7-methoxyflavanoneAspergillus nigerAspergillus ochraceusPenicillium chermesinum |
| spellingShingle | Edyta Kostrzewa-Susłow Tomasz Janeczko Microbial Transformations of 7-Methoxyflavanone Molecules biotransformation 7-methoxyflavanone Aspergillus niger Aspergillus ochraceus Penicillium chermesinum |
| title | Microbial Transformations of 7-Methoxyflavanone |
| title_full | Microbial Transformations of 7-Methoxyflavanone |
| title_fullStr | Microbial Transformations of 7-Methoxyflavanone |
| title_full_unstemmed | Microbial Transformations of 7-Methoxyflavanone |
| title_short | Microbial Transformations of 7-Methoxyflavanone |
| title_sort | microbial transformations of 7 methoxyflavanone |
| topic | biotransformation 7-methoxyflavanone Aspergillus niger Aspergillus ochraceus Penicillium chermesinum |
| url | http://www.mdpi.com/1420-3049/17/12/14810 |
| work_keys_str_mv | AT edytakostrzewasusłow microbialtransformationsof7methoxyflavanone AT tomaszjaneczko microbialtransformationsof7methoxyflavanone |