NSD Overexpression in the Fat Body Increases Antimicrobial Peptide Production by the Immune Deficiency Pathway in <i>Drosophila</i>
Nuclear receptor-binding SET domain-containing protein 1 (NSD1) inactivation in tumor cells contributes to an immune-cold phenotype, indicating its potential association with immune disturbances. <i>Drosophila</i> NSD is a homolog of the human NSD1. Thus, in this study, we investigated t...
Main Authors: | Chihyun Won, Kyungju Nam, Donghee Ko, Byungjun Kang, Im-Soon Lee |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-05-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/9/8443 |
Similar Items
-
The first pineoblastoma case report of a patient with Sotos syndrome harboring NSD1 germline mutation
by: Xizan Yue, et al.
Published: (2024-03-01) -
Molecular Analysis and Reclassification of NSD1 Gene Variants in a Cohort of Patients with Clinical Suspicion of Sotos Syndrome
by: Barbara Testa, et al.
Published: (2023-01-01) -
NSD1: A Lysine Methyltransferase between Developmental Disorders and Cancer
by: Samantha Tauchmann, et al.
Published: (2021-08-01) -
NSD1 gene evolves under episodic selection within primates and mutations of specific exons in humans cause Sotos syndrome
by: Vanessa I. Romero, et al.
Published: (2022-12-01) -
A novel nonsense variant in NSD1 gene in a female child with Sotos syndrome: A case report and literature review
by: Xinting Liu, et al.
Published: (2023-12-01)