Proliferative verrucous leukoplakia: Case report and a comprehensive review of literature
Proliferative verrucous leukoplakia (PVL) is a rare form of oral leukoplakia, which was first described in 1985 by Hansen et al. Since then, various published case series have presented PVL as a disease with aggressive biological behavior due to its high probability of recurrence and a high rate of...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Saudi Journal of Oral Sciences |
| Subjects: | |
| Online Access: | http://www.saudijos.org//article.asp?issn=1658-6816;year=2015;volume=2;issue=2;spage=103;epage=105;aulast=Raghuvanshi |
| _version_ | 1811217026613510144 |
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| author | Vikalp Raghuvanshi Kriti Shrivastava Hina Handa |
| author_facet | Vikalp Raghuvanshi Kriti Shrivastava Hina Handa |
| author_sort | Vikalp Raghuvanshi |
| collection | DOAJ |
| description | Proliferative verrucous leukoplakia (PVL) is a rare form of oral leukoplakia, which was first described in 1985 by Hansen et al. Since then, various published case series have presented PVL as a disease with aggressive biological behavior due to its high probability of recurrence and a high rate of malignant transformation, usually higher than 70%. PVL is a long-term progressive condition, and tends to become multifocal with a progressive deterioration of the lesions, making it more and more difficult to control. According to reported literature tobacco use does not seem to have a significant influence on the appearance or progression of PVL as these lesions may occur both in smokers and nonsmokers. At present, the etiology of PVL remains unclear as well as its management and diagnosis, which is still retrospective, late and poorly defined, lacking consensus criteria.
Here we present a case of PVL and intend to discuss the key features related to etiology, diagnosis, management and prognosis of proliferative verrucous leukoplakia. |
| first_indexed | 2024-04-12T06:47:01Z |
| format | Article |
| id | doaj.art-78e980acca614cc29128ef94c23c72da |
| institution | Directory Open Access Journal |
| issn | 1658-6816 |
| language | English |
| last_indexed | 2024-04-12T06:47:01Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Oral Sciences |
| spelling | doaj.art-78e980acca614cc29128ef94c23c72da2022-12-22T03:43:29ZengWolters Kluwer Medknow PublicationsSaudi Journal of Oral Sciences1658-68162015-01-012210310510.4103/1658-6816.160779Proliferative verrucous leukoplakia: Case report and a comprehensive review of literatureVikalp RaghuvanshiKriti ShrivastavaHina HandaProliferative verrucous leukoplakia (PVL) is a rare form of oral leukoplakia, which was first described in 1985 by Hansen et al. Since then, various published case series have presented PVL as a disease with aggressive biological behavior due to its high probability of recurrence and a high rate of malignant transformation, usually higher than 70%. PVL is a long-term progressive condition, and tends to become multifocal with a progressive deterioration of the lesions, making it more and more difficult to control. According to reported literature tobacco use does not seem to have a significant influence on the appearance or progression of PVL as these lesions may occur both in smokers and nonsmokers. At present, the etiology of PVL remains unclear as well as its management and diagnosis, which is still retrospective, late and poorly defined, lacking consensus criteria. Here we present a case of PVL and intend to discuss the key features related to etiology, diagnosis, management and prognosis of proliferative verrucous leukoplakia.http://www.saudijos.org//article.asp?issn=1658-6816;year=2015;volume=2;issue=2;spage=103;epage=105;aulast=RaghuvanshiLeukoplakiaproliferativemultifocal |
| spellingShingle | Vikalp Raghuvanshi Kriti Shrivastava Hina Handa Proliferative verrucous leukoplakia: Case report and a comprehensive review of literature Saudi Journal of Oral Sciences Leukoplakia proliferative multifocal |
| title | Proliferative verrucous leukoplakia: Case report and a comprehensive review of literature |
| title_full | Proliferative verrucous leukoplakia: Case report and a comprehensive review of literature |
| title_fullStr | Proliferative verrucous leukoplakia: Case report and a comprehensive review of literature |
| title_full_unstemmed | Proliferative verrucous leukoplakia: Case report and a comprehensive review of literature |
| title_short | Proliferative verrucous leukoplakia: Case report and a comprehensive review of literature |
| title_sort | proliferative verrucous leukoplakia case report and a comprehensive review of literature |
| topic | Leukoplakia proliferative multifocal |
| url | http://www.saudijos.org//article.asp?issn=1658-6816;year=2015;volume=2;issue=2;spage=103;epage=105;aulast=Raghuvanshi |
| work_keys_str_mv | AT vikalpraghuvanshi proliferativeverrucousleukoplakiacasereportandacomprehensivereviewofliterature AT kritishrivastava proliferativeverrucousleukoplakiacasereportandacomprehensivereviewofliterature AT hinahanda proliferativeverrucousleukoplakiacasereportandacomprehensivereviewofliterature |