Chromosome Aberrations as Bioindicators of Environmental Genotoxicity
Due to the exposure to various potentially genotoxic xenobiotics, derived from recent war activities such as NATO air strikes with antitank ammunition containing depleted uranium, we have evaluated chromosome aberrations in 84 peripheral blood samples from three local populations. One population sa...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2007-11-01
|
Series: | Biomolecules & Biomedicine |
Subjects: | |
Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/3019 |
_version_ | 1797260829102440448 |
---|---|
author | Slavica Ibrulj Sanin Haverić Anja Haverić |
author_facet | Slavica Ibrulj Sanin Haverić Anja Haverić |
author_sort | Slavica Ibrulj |
collection | DOAJ |
description |
Due to the exposure to various potentially genotoxic xenobiotics, derived from recent war activities such as NATO air strikes with antitank ammunition containing depleted uranium, we have evaluated chromosome aberrations in 84 peripheral blood samples from three local populations. One population sample included 30 individuals who lived in the Sarajevo area during and after the war (exposed to potential genotoxins), second population was presented with 26 employees of the tank repair facility in Hadžići (target of NATO air strikes), and 28 inhabitants of Posušje (not exposed to war-related activities) were treated as sample of control population. The mean of chromosome aberration frequencies for the population from Hadžići was significantly higher than the frequencies for the two other populations. Point bi-serial coefficient analysis did not reveal any relationship between the frequencies of chromosome aberrations and smoking habits or gender. Results suggest that depleted uranium could be a risk factor for human health.
|
first_indexed | 2024-04-24T23:31:32Z |
format | Article |
id | doaj.art-78ea85cb185247ee9509b27d8b300f35 |
institution | Directory Open Access Journal |
issn | 2831-0896 2831-090X |
language | English |
last_indexed | 2024-04-24T23:31:32Z |
publishDate | 2007-11-01 |
publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
record_format | Article |
series | Biomolecules & Biomedicine |
spelling | doaj.art-78ea85cb185247ee9509b27d8b300f352024-03-15T14:38:18ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2007-11-017410.17305/bjbms.2007.3019604Chromosome Aberrations as Bioindicators of Environmental GenotoxicitySlavica Ibrulj0Sanin Haverić1Anja Haverić2Faculty of Medicine, University of Sarajevo Institute for Genetic Engineering and BiotechnologyInstitute for Genetic Engineering and BiotechnologyInstitute for Genetic Engineering and Biotechnology Due to the exposure to various potentially genotoxic xenobiotics, derived from recent war activities such as NATO air strikes with antitank ammunition containing depleted uranium, we have evaluated chromosome aberrations in 84 peripheral blood samples from three local populations. One population sample included 30 individuals who lived in the Sarajevo area during and after the war (exposed to potential genotoxins), second population was presented with 26 employees of the tank repair facility in Hadžići (target of NATO air strikes), and 28 inhabitants of Posušje (not exposed to war-related activities) were treated as sample of control population. The mean of chromosome aberration frequencies for the population from Hadžići was significantly higher than the frequencies for the two other populations. Point bi-serial coefficient analysis did not reveal any relationship between the frequencies of chromosome aberrations and smoking habits or gender. Results suggest that depleted uranium could be a risk factor for human health. https://www.bjbms.org/ojs/index.php/bjbms/article/view/3019environmental genotoxinsdepleted uraniumhuman lymphocytes |
spellingShingle | Slavica Ibrulj Sanin Haverić Anja Haverić Chromosome Aberrations as Bioindicators of Environmental Genotoxicity Biomolecules & Biomedicine environmental genotoxins depleted uranium human lymphocytes |
title | Chromosome Aberrations as Bioindicators of Environmental Genotoxicity |
title_full | Chromosome Aberrations as Bioindicators of Environmental Genotoxicity |
title_fullStr | Chromosome Aberrations as Bioindicators of Environmental Genotoxicity |
title_full_unstemmed | Chromosome Aberrations as Bioindicators of Environmental Genotoxicity |
title_short | Chromosome Aberrations as Bioindicators of Environmental Genotoxicity |
title_sort | chromosome aberrations as bioindicators of environmental genotoxicity |
topic | environmental genotoxins depleted uranium human lymphocytes |
url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/3019 |
work_keys_str_mv | AT slavicaibrulj chromosomeaberrationsasbioindicatorsofenvironmentalgenotoxicity AT saninhaveric chromosomeaberrationsasbioindicatorsofenvironmentalgenotoxicity AT anjahaveric chromosomeaberrationsasbioindicatorsofenvironmentalgenotoxicity |