Chromosome Aberrations as Bioindicators of Environmental Genotoxicity

Due to the exposure to various potentially genotoxic xenobiotics, derived from recent war activities such as NATO air strikes with antitank ammunition containing depleted uranium, we have evaluated chromosome aberrations in 84 peripheral blood samples from three local populations. One population sa...

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Main Authors: Slavica Ibrulj, Sanin Haverić, Anja Haverić
Format: Article
Language:English
Published: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2007-11-01
Series:Biomolecules & Biomedicine
Subjects:
Online Access:https://www.bjbms.org/ojs/index.php/bjbms/article/view/3019
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author Slavica Ibrulj
Sanin Haverić
Anja Haverić
author_facet Slavica Ibrulj
Sanin Haverić
Anja Haverić
author_sort Slavica Ibrulj
collection DOAJ
description Due to the exposure to various potentially genotoxic xenobiotics, derived from recent war activities such as NATO air strikes with antitank ammunition containing depleted uranium, we have evaluated chromosome aberrations in 84 peripheral blood samples from three local populations. One population sample included 30 individuals who lived in the Sarajevo area during and after the war (exposed to potential genotoxins), second population was presented with 26 employees of the tank repair facility in Hadžići (target of NATO air strikes), and 28 inhabitants of Posušje (not exposed to war-related activities) were treated as sample of control population. The mean of chromosome aberration frequencies for the population from Hadžići was significantly higher than the frequencies for the two other populations. Point bi-serial coefficient analysis did not reveal any relationship between the frequencies of chromosome aberrations and smoking habits or gender. Results suggest that depleted uranium could be a risk factor for human health.
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spelling doaj.art-78ea85cb185247ee9509b27d8b300f352024-03-15T14:38:18ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2007-11-017410.17305/bjbms.2007.3019604Chromosome Aberrations as Bioindicators of Environmental GenotoxicitySlavica Ibrulj0Sanin Haverić1Anja Haverić2Faculty of Medicine, University of Sarajevo Institute for Genetic Engineering and BiotechnologyInstitute for Genetic Engineering and BiotechnologyInstitute for Genetic Engineering and Biotechnology Due to the exposure to various potentially genotoxic xenobiotics, derived from recent war activities such as NATO air strikes with antitank ammunition containing depleted uranium, we have evaluated chromosome aberrations in 84 peripheral blood samples from three local populations. One population sample included 30 individuals who lived in the Sarajevo area during and after the war (exposed to potential genotoxins), second population was presented with 26 employees of the tank repair facility in Hadžići (target of NATO air strikes), and 28 inhabitants of Posušje (not exposed to war-related activities) were treated as sample of control population. The mean of chromosome aberration frequencies for the population from Hadžići was significantly higher than the frequencies for the two other populations. Point bi-serial coefficient analysis did not reveal any relationship between the frequencies of chromosome aberrations and smoking habits or gender. Results suggest that depleted uranium could be a risk factor for human health. https://www.bjbms.org/ojs/index.php/bjbms/article/view/3019environmental genotoxinsdepleted uraniumhuman lymphocytes
spellingShingle Slavica Ibrulj
Sanin Haverić
Anja Haverić
Chromosome Aberrations as Bioindicators of Environmental Genotoxicity
Biomolecules & Biomedicine
environmental genotoxins
depleted uranium
human lymphocytes
title Chromosome Aberrations as Bioindicators of Environmental Genotoxicity
title_full Chromosome Aberrations as Bioindicators of Environmental Genotoxicity
title_fullStr Chromosome Aberrations as Bioindicators of Environmental Genotoxicity
title_full_unstemmed Chromosome Aberrations as Bioindicators of Environmental Genotoxicity
title_short Chromosome Aberrations as Bioindicators of Environmental Genotoxicity
title_sort chromosome aberrations as bioindicators of environmental genotoxicity
topic environmental genotoxins
depleted uranium
human lymphocytes
url https://www.bjbms.org/ojs/index.php/bjbms/article/view/3019
work_keys_str_mv AT slavicaibrulj chromosomeaberrationsasbioindicatorsofenvironmentalgenotoxicity
AT saninhaveric chromosomeaberrationsasbioindicatorsofenvironmentalgenotoxicity
AT anjahaveric chromosomeaberrationsasbioindicatorsofenvironmentalgenotoxicity