Decreased Expression of IL‐35 and Its Receptor Contributes to Impaired Megakaryopoiesis in the Pathogenesis of Immune Thrombocytopenia

Decreased Expression of IL‐35 and Its Receptor Contributes to Impaired Megakaryopoiesis in the Pathogenesis of Immune Thrombocytopenia

Abstract Recent findings have shown that the level of interleukin‐35 (IL‐35) is abnormal in several autoimmune diseases. Nonetheless, whether IL‐35 participates in the pathogenesis of immune thrombocytopenia (ITP) remains unclear. The current study investigates whether IL‐35 modulates megakaryopoies...

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Bibliographic Details
Main Authors: Xuan Cai, Ruo‐Yun Gui, Jin Wu, Chen‐Cong Wang, Xiao‐Lu Zhu, Hai‐Xia Fu, Xiao‐Hui Zhang
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
iguratimod
IL‐35
iTr35
megakaryopoiesis
mesenchymal stem cells
Online Access:https://doi.org/10.1002/advs.202305798

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