Modulating effect of Cu(II) complexes with enamine and tetrazole derivatives on CYP2C and CYP3A and their cytotoxic and antiproliferative properties in HepG2 spheroids
CYP2C and CYP3A cytochromes are induced by a variety of compounds and affect the pharmacokinetics and pharmacodynamics of a large number of drugs. Currently, the possibility of using copper coordination compounds in antitumor therapy is being actively studied. Evaluation of potential interactions be...
Main Authors: | , , , |
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Format: | Article |
Language: | Russian |
Published: |
Scientific Сentre for Family Health and Human Reproduction Problems
2022-12-01
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Series: | Acta Biomedica Scientifica |
Subjects: | |
Online Access: | https://www.actabiomedica.ru/jour/article/view/3823 |