Widefield choroidal vasculature associated with future condition of subretinal fluid in central serous chorioretinopathy
Purpose: To examine choroidal angiographic features in the posterior pole associated with resolution or persistency of subretinal fluid (SRF) in eyes with central serous chorioretinopathy (CSC). Design: Observational case series. Methods: Twenty-nine patients with treatment-naïve CSC were divided in...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-08-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023056499 |
| _version_ | 1827856225276002304 |
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| author | Takahiro Kogo Yuki Muraoka Masaharu Ishikura Naomi Nishigori Naoko Ueda-Arakawa Manabu Miyata Hiroshi Tamura Masayuki Hata Ayako Takahashi Masahiro Miyake Akitaka Tsujikawa |
| author_facet | Takahiro Kogo Yuki Muraoka Masaharu Ishikura Naomi Nishigori Naoko Ueda-Arakawa Manabu Miyata Hiroshi Tamura Masayuki Hata Ayako Takahashi Masahiro Miyake Akitaka Tsujikawa |
| author_sort | Takahiro Kogo |
| collection | DOAJ |
| description | Purpose: To examine choroidal angiographic features in the posterior pole associated with resolution or persistency of subretinal fluid (SRF) in eyes with central serous chorioretinopathy (CSC). Design: Observational case series. Methods: Twenty-nine patients with treatment-naïve CSC were divided into two groups based on the presence or absence of SRF 3 months after the initial visit (month 3) without any treatment. Using enhanced depth imaging of widefield swept-source optical coherence tomography, the choroidal thickness (CT), vessel density (VD), and vessel diameter index (VDI) in the superotemporal and inferotemporal subfields on the temporal side of the 18-mm circle from the disc were measured at the initial visit. We calculated the vertical difference in CT and other choroidal angiographic parameters and evaluated their association with the SRF condition at 3 months. Results: The SRF-resolved and SRF-persistent groups included 10 and 19 patients, respectively. At the initial visit, sex, age, axial length, symptom duration, the logarithm of the minimum angle of resolution visual acuity, and foveal thickness were not significantly different between the two groups. The SRF status at month 3 was not associated with the vertical difference in CT and choroidal VD (P = .614, .065, respectively). However, the vertical difference in choroidal VDI was positively associated with the future presence of SRF (P = .017). Conclusions: Vertically asymmetric dilation of choroidal vessels in the posterior pole may be a vasculature feature associated with SRF from CSC and may be a good predictor of future SRF status. |
| first_indexed | 2024-03-12T12:22:39Z |
| format | Article |
| id | doaj.art-78f1262964864b469d03125f18c6680a |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-12T12:22:39Z |
| publishDate | 2023-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-78f1262964864b469d03125f18c6680a2023-08-30T05:51:19ZengElsevierHeliyon2405-84402023-08-0198e18441Widefield choroidal vasculature associated with future condition of subretinal fluid in central serous chorioretinopathyTakahiro Kogo0Yuki Muraoka1Masaharu Ishikura2Naomi Nishigori3Naoko Ueda-Arakawa4Manabu Miyata5Hiroshi Tamura6Masayuki Hata7Ayako Takahashi8Masahiro Miyake9Akitaka Tsujikawa10Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, JapanCorresponding author. Department of Ophthalmology, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, 606-8507, Japan.; Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, JapanDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, JapanDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, JapanDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, JapanDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, JapanDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, JapanDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, JapanDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, JapanDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, JapanDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, JapanPurpose: To examine choroidal angiographic features in the posterior pole associated with resolution or persistency of subretinal fluid (SRF) in eyes with central serous chorioretinopathy (CSC). Design: Observational case series. Methods: Twenty-nine patients with treatment-naïve CSC were divided into two groups based on the presence or absence of SRF 3 months after the initial visit (month 3) without any treatment. Using enhanced depth imaging of widefield swept-source optical coherence tomography, the choroidal thickness (CT), vessel density (VD), and vessel diameter index (VDI) in the superotemporal and inferotemporal subfields on the temporal side of the 18-mm circle from the disc were measured at the initial visit. We calculated the vertical difference in CT and other choroidal angiographic parameters and evaluated their association with the SRF condition at 3 months. Results: The SRF-resolved and SRF-persistent groups included 10 and 19 patients, respectively. At the initial visit, sex, age, axial length, symptom duration, the logarithm of the minimum angle of resolution visual acuity, and foveal thickness were not significantly different between the two groups. The SRF status at month 3 was not associated with the vertical difference in CT and choroidal VD (P = .614, .065, respectively). However, the vertical difference in choroidal VDI was positively associated with the future presence of SRF (P = .017). Conclusions: Vertically asymmetric dilation of choroidal vessels in the posterior pole may be a vasculature feature associated with SRF from CSC and may be a good predictor of future SRF status.http://www.sciencedirect.com/science/article/pii/S2405844023056499Central serous chorioretinopathyWidefield swept-source optical coherence tomographyEnhanced depth imagingSubretinal fluidSubretinal fluid prognosisChoroidal thickness |
| spellingShingle | Takahiro Kogo Yuki Muraoka Masaharu Ishikura Naomi Nishigori Naoko Ueda-Arakawa Manabu Miyata Hiroshi Tamura Masayuki Hata Ayako Takahashi Masahiro Miyake Akitaka Tsujikawa Widefield choroidal vasculature associated with future condition of subretinal fluid in central serous chorioretinopathy Heliyon Central serous chorioretinopathy Widefield swept-source optical coherence tomography Enhanced depth imaging Subretinal fluid Subretinal fluid prognosis Choroidal thickness |
| title | Widefield choroidal vasculature associated with future condition of subretinal fluid in central serous chorioretinopathy |
| title_full | Widefield choroidal vasculature associated with future condition of subretinal fluid in central serous chorioretinopathy |
| title_fullStr | Widefield choroidal vasculature associated with future condition of subretinal fluid in central serous chorioretinopathy |
| title_full_unstemmed | Widefield choroidal vasculature associated with future condition of subretinal fluid in central serous chorioretinopathy |
| title_short | Widefield choroidal vasculature associated with future condition of subretinal fluid in central serous chorioretinopathy |
| title_sort | widefield choroidal vasculature associated with future condition of subretinal fluid in central serous chorioretinopathy |
| topic | Central serous chorioretinopathy Widefield swept-source optical coherence tomography Enhanced depth imaging Subretinal fluid Subretinal fluid prognosis Choroidal thickness |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023056499 |
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