Case report: Targeting the PD-1 receptor and genetic mutations validated in primary histiocytic sarcoma with hemophagocytic lymphohistiocytosis

Case report: Targeting the PD-1 receptor and genetic mutations validated in primary histiocytic sarcoma with hemophagocytic lymphohistiocytosis

Histiocytic sarcoma (HS) is a rare hematological malignancy with limited treatment options, and it is also prone to complications such as hemophagocytic lymphohistiocytosis (HLH) in the later stages of the disease, leading to difficulties in treatment and poor prognosis. It highlights the importance...

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Bibliographic Details
Main Authors: Yan Zhao, Yating Deng, Yi Jiang, Wenli Zheng, Yanlin Tan, Zhiwu Yang, Zhihua Wang, Feng Xu, Zhao Cheng, Lingli Yuan, Hongling Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
histiocytic sarcoma
hemophagocytic lymphohistiocytosis
sequencing
programmed death-ligand 1 (PD-L1)
targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1127599/full

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