Trabecular bone score in obese patients with and without diabetes
The link between obesity, diabetes and bone metabolism is quite complex and not entirely clear. Although many clinical and epidemiological studies demonstrate that obesity enhances bone mineral density, its effect on bone microarchitecture is uncertain. The objective of this study was to examine th...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2024-02-01
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| Series: | Italian Journal of Medicine |
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| Online Access: | https://italjmed.org/index.php/ijm/article/view/1696 |
| _version_ | 1797323917900120064 |
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| author | Gordana Dzeletovic Aleksandar Jovanovic Tatjana Novakovic Snezana Markovic-Jovanovic Emilija Novakovic Anja Dzeletovic Milena Lukić Biljana Kostic-Inic Sanja Jovanovic Miljan Jankovic |
| author_facet | Gordana Dzeletovic Aleksandar Jovanovic Tatjana Novakovic Snezana Markovic-Jovanovic Emilija Novakovic Anja Dzeletovic Milena Lukić Biljana Kostic-Inic Sanja Jovanovic Miljan Jankovic |
| author_sort | Gordana Dzeletovic |
| collection | DOAJ |
| description |
The link between obesity, diabetes and bone metabolism is quite complex and not entirely clear. Although many clinical and epidemiological studies demonstrate that obesity enhances bone mineral density, its effect on bone microarchitecture is uncertain. The objective of this study was to examine the bone microarchitecture in obese patients with and without diabetes. The study included 119 individuals with ages from 30 to 50. Participants were divided into three groups: obese patients, obese diabetic patients, and a healthy control group. Results showed that obesity has a positive effect on trabecular bone score (TBS). Diabetes and obesity have a significant interactive impact on bone microarchitecture (TBS). Furthermore, HbA1c influences TBS in both obese diabetic patients and obese non-diabetic subjects. In contrast to the majority of studies, we found that obesity positively influenced TBS. TBS was inversely related to HbA1c levels in obese type 2 diabetics. Diabetes and obesity have a significant interactive impact on bone structure, in particular on bone microarchitecture.
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| first_indexed | 2024-03-08T05:35:57Z |
| format | Article |
| id | doaj.art-78f48ad758984289908a04b4bf850bd4 |
| institution | Directory Open Access Journal |
| issn | 1877-9344 1877-9352 |
| language | English |
| last_indexed | 2024-03-08T05:35:57Z |
| publishDate | 2024-02-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Italian Journal of Medicine |
| spelling | doaj.art-78f48ad758984289908a04b4bf850bd42024-02-05T20:36:27ZengPAGEPress PublicationsItalian Journal of Medicine1877-93441877-93522024-02-0118110.4081/itjm.2024.1696Trabecular bone score in obese patients with and without diabetesGordana Dzeletovic0Aleksandar Jovanovic1Tatjana Novakovic2Snezana Markovic-Jovanovic3Emilija Novakovic4Anja Dzeletovic5Milena Lukić6Biljana Kostic-Inic7Sanja Jovanovic8Miljan Jankovic9Military Hospital, Novi SadFaculty of Medicine, University of Pristina - Kosovska MitrovicaFaculty of Medicine, University of Pristina - Kosovska MitrovicaFaculty of Medicine, University of Pristina - Kosovska MitrovicaFaculty of Medicine, University of Pristina - Kosovska MitrovicaFaculty of Medicine, Novi SadCord IPS, Novi SadClinical Hospital Centre, Pristina, GračanicaFaculty of Medicine, University of Pristina - Kosovska MitrovicaFaculty of Medicine, University of Pristina - Kosovska Mitrovica The link between obesity, diabetes and bone metabolism is quite complex and not entirely clear. Although many clinical and epidemiological studies demonstrate that obesity enhances bone mineral density, its effect on bone microarchitecture is uncertain. The objective of this study was to examine the bone microarchitecture in obese patients with and without diabetes. The study included 119 individuals with ages from 30 to 50. Participants were divided into three groups: obese patients, obese diabetic patients, and a healthy control group. Results showed that obesity has a positive effect on trabecular bone score (TBS). Diabetes and obesity have a significant interactive impact on bone microarchitecture (TBS). Furthermore, HbA1c influences TBS in both obese diabetic patients and obese non-diabetic subjects. In contrast to the majority of studies, we found that obesity positively influenced TBS. TBS was inversely related to HbA1c levels in obese type 2 diabetics. Diabetes and obesity have a significant interactive impact on bone structure, in particular on bone microarchitecture. https://italjmed.org/index.php/ijm/article/view/1696Obesitydiabetestrabecular bone density |
| spellingShingle | Gordana Dzeletovic Aleksandar Jovanovic Tatjana Novakovic Snezana Markovic-Jovanovic Emilija Novakovic Anja Dzeletovic Milena Lukić Biljana Kostic-Inic Sanja Jovanovic Miljan Jankovic Trabecular bone score in obese patients with and without diabetes Italian Journal of Medicine Obesity diabetes trabecular bone density |
| title | Trabecular bone score in obese patients with and without diabetes |
| title_full | Trabecular bone score in obese patients with and without diabetes |
| title_fullStr | Trabecular bone score in obese patients with and without diabetes |
| title_full_unstemmed | Trabecular bone score in obese patients with and without diabetes |
| title_short | Trabecular bone score in obese patients with and without diabetes |
| title_sort | trabecular bone score in obese patients with and without diabetes |
| topic | Obesity diabetes trabecular bone density |
| url | https://italjmed.org/index.php/ijm/article/view/1696 |
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