Propofol infusions using a human target controlled infusion (TCI) pump in chimpanzees (Pan troglodytes)

Propofol infusions using a human target controlled infusion (TCI) pump in chimpanzees (Pan troglodytes)

Abstract Chimpanzees are genetically and physiologically similar to humans. Several pharmacokinetic models of propofol are available and target controlled infusion (TCI) of propofol is established in humans, but not in chimpanzees. The purpose of this study was to investigate if human pharmacokineti...

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Bibliographic Details
Main Authors: T. Miyabe-Nishiwaki, A. Kaneko, A. Yamanaka, N. Maeda, J. Suzuki, M. Tomonaga, T. Matsuzawa, K. Muta, R. Nishimura, I. Yajima, D. J. Eleveld, A. R. Absalom, K. Masui
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79914-7

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