Hemoglobin E disorders in Eastern Uttar Pradesh
The distribution of hemoglobin E (α<sub>2</sub>β2<sup> 26Glu ®Lys</sup> ) is mostly restricted to Northeastern India. While evaluating the patients of jaundice, we came across two cases of hemoglobin E (Hb E) disorders. The first case is in a 22-y...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2009-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=1;spage=110;epage=112;aulast=Patne |
| _version_ | 1819092816706404352 |
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| author | Patne Shashikant Shukla Jyoti |
| author_facet | Patne Shashikant Shukla Jyoti |
| author_sort | Patne Shashikant |
| collection | DOAJ |
| description | The distribution of hemoglobin E (α<sub>2</sub>β2<sup> 26Glu ®Lys</sup> ) is mostly restricted to Northeastern India. While evaluating the patients of jaundice, we came across two cases of hemoglobin E (Hb E) disorders. The first case is in a 22-year-old Bengali male and the second case of Hb E/β thalassemia in a 5-year-old Hindu boy. The family study revealed Hb E trait in both the parents of Case 1, whereas in Case 2, the father was found to have Hb E trait and the mother had β -thalassemia minor, thus confirming the diagnosis. Herein, we present the laboratory diagnosis and comparative data of the spectrum of Hb E disorders (i.e., heterozygous Hb E trait, homozygous Hb E disease and compound heterozygous Hb E/β -thalassemia) that was found in our index cases and their parents. |
| first_indexed | 2024-12-21T23:01:38Z |
| format | Article |
| id | doaj.art-78fa10955f1d44559609da665b07c331 |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-12-21T23:01:38Z |
| publishDate | 2009-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-78fa10955f1d44559609da665b07c3312022-12-21T18:47:17ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292009-01-01521110112Hemoglobin E disorders in Eastern Uttar PradeshPatne ShashikantShukla JyotiThe distribution of hemoglobin E (α<sub>2</sub>β2<sup> 26Glu ®Lys</sup> ) is mostly restricted to Northeastern India. While evaluating the patients of jaundice, we came across two cases of hemoglobin E (Hb E) disorders. The first case is in a 22-year-old Bengali male and the second case of Hb E/β thalassemia in a 5-year-old Hindu boy. The family study revealed Hb E trait in both the parents of Case 1, whereas in Case 2, the father was found to have Hb E trait and the mother had β -thalassemia minor, thus confirming the diagnosis. Herein, we present the laboratory diagnosis and comparative data of the spectrum of Hb E disorders (i.e., heterozygous Hb E trait, homozygous Hb E disease and compound heterozygous Hb E/β -thalassemia) that was found in our index cases and their parents.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=1;spage=110;epage=112;aulast=PatneHemoglobin EHb E/β -thalassemiajaundice |
| spellingShingle | Patne Shashikant Shukla Jyoti Hemoglobin E disorders in Eastern Uttar Pradesh Indian Journal of Pathology and Microbiology Hemoglobin E Hb E/β -thalassemia jaundice |
| title | Hemoglobin E disorders in Eastern Uttar Pradesh |
| title_full | Hemoglobin E disorders in Eastern Uttar Pradesh |
| title_fullStr | Hemoglobin E disorders in Eastern Uttar Pradesh |
| title_full_unstemmed | Hemoglobin E disorders in Eastern Uttar Pradesh |
| title_short | Hemoglobin E disorders in Eastern Uttar Pradesh |
| title_sort | hemoglobin e disorders in eastern uttar pradesh |
| topic | Hemoglobin E Hb E/β -thalassemia jaundice |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2009;volume=52;issue=1;spage=110;epage=112;aulast=Patne |
| work_keys_str_mv | AT patneshashikant hemoglobinedisordersineasternuttarpradesh AT shuklajyoti hemoglobinedisordersineasternuttarpradesh |