Low Dose Gamma Irradiation of Trypanosoma evansi Parasites Identifies Molecular Changes That Occur to Repair Radiation Damage and Gene Transcripts That May Be Involved in Establishing Disease in Mice Post-Irradiation

Low Dose Gamma Irradiation of Trypanosoma evansi Parasites Identifies Molecular Changes That Occur to Repair Radiation Damage and Gene Transcripts That May Be Involved in Establishing Disease in Mice Post-Irradiation

The protozoan parasite Trypanosoma evansi is responsible for causing surra in a variety of mammalian hosts and is spread by many vectors over a wide geographical area making it an ideal target for irradiation as a tool to study the initial events that occur during infection. Parasites irradiated at...

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Bibliographic Details
Main Authors: Richard T. Kangethe, Eva M. Winger, Tirumala Bharani K. Settypalli, Sneha Datta, Viskam Wijewardana, Charles E. Lamien, Hermann Unger, Theresa H.T. Coetzer, Giovanni Cattoli, Adama Diallo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
Trypanosoma evansi
gamma irradiation
TryMS array
vaccine
surra
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.852091/full

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