Revealing molecular mechanisms by integrating high-dimensional functional screens with protein interaction data.
Functional genomics screens using multi-parametric assays are powerful approaches for identifying genes involved in particular cellular processes. However, they suffer from problems like noise, and often provide little insight into molecular mechanisms. A bottleneck for addressing these issues is th...
Main Authors: | Angela Simeone, Giovanni Marsico, Claudio Collinet, Thierry Galvez, Yannis Kalaidzidis, Marino Zerial, Andreas Beyer |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-09-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4154648?pdf=render |
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