The safe interval time of cold bloody cardioplegic solution transfusion during CABG

Background: During CABG cardioplefic solution is used for cardiac arrest and myocardial protection but there is no defined safety interval time for cardioplegia infusion. Measuremen of the metabolite release from myocardial cells in coronary sinus implicateis accurate protective effect and safety in...

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Main Authors: Ebrahim Shafiei, Zinat Fouladi, Parham Shafiei
Format: Article
Language:English
Published: Bushehr University of Medical Sciences 2015-05-01
Series:Iranian South Medical Journal
Subjects:
Online Access:http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-588&slc_lang=en&sid=1
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author Ebrahim Shafiei
Zinat Fouladi
Parham Shafiei
author_facet Ebrahim Shafiei
Zinat Fouladi
Parham Shafiei
author_sort Ebrahim Shafiei
collection DOAJ
description Background: During CABG cardioplefic solution is used for cardiac arrest and myocardial protection but there is no defined safety interval time for cardioplegia infusion. Measuremen of the metabolite release from myocardial cells in coronary sinus implicateis accurate protective effect and safety interval of cardioplegia Materials and Methods: Thirteen patients that were scaduled for CABG cold blood cardioplegia transfused via aortic root. Coronary sinus blood samples were taken before and after cross clamping of the aorta at the times of 7, 14 and 20 minutes. The samples were analyzed for pH and lactate immediately. Results: The pH and lactate concentration in coronary at the time of 15 minute after the second dose of transfusion of blood cardioplegia were out of the range of acceptable level (pH=7.22±0.047 lactate=21±2.859mg/dl ρ=0.02). Conclusion: This study indicates that safe interval time between the first and second dose of cardioplegia transfusion was 20 minute and the between second and third dose was 15 minutes.
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spelling doaj.art-78ffc70509664f2ab9f700fb8934163f2022-12-21T23:37:35ZengBushehr University of Medical SciencesIranian South Medical Journal1735-43741735-69542015-05-01182314322The safe interval time of cold bloody cardioplegic solution transfusion during CABGEbrahim Shafiei0Zinat Fouladi1Parham Shafiei2 Background: During CABG cardioplefic solution is used for cardiac arrest and myocardial protection but there is no defined safety interval time for cardioplegia infusion. Measuremen of the metabolite release from myocardial cells in coronary sinus implicateis accurate protective effect and safety interval of cardioplegia Materials and Methods: Thirteen patients that were scaduled for CABG cold blood cardioplegia transfused via aortic root. Coronary sinus blood samples were taken before and after cross clamping of the aorta at the times of 7, 14 and 20 minutes. The samples were analyzed for pH and lactate immediately. Results: The pH and lactate concentration in coronary at the time of 15 minute after the second dose of transfusion of blood cardioplegia were out of the range of acceptable level (pH=7.22±0.047 lactate=21±2.859mg/dl ρ=0.02). Conclusion: This study indicates that safe interval time between the first and second dose of cardioplegia transfusion was 20 minute and the between second and third dose was 15 minutes.http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-588&slc_lang=en&sid=1myocardial protection cardioplegia coronary sinus pH lactate
spellingShingle Ebrahim Shafiei
Zinat Fouladi
Parham Shafiei
The safe interval time of cold bloody cardioplegic solution transfusion during CABG
Iranian South Medical Journal
myocardial protection
cardioplegia
coronary sinus
pH
lactate
title The safe interval time of cold bloody cardioplegic solution transfusion during CABG
title_full The safe interval time of cold bloody cardioplegic solution transfusion during CABG
title_fullStr The safe interval time of cold bloody cardioplegic solution transfusion during CABG
title_full_unstemmed The safe interval time of cold bloody cardioplegic solution transfusion during CABG
title_short The safe interval time of cold bloody cardioplegic solution transfusion during CABG
title_sort safe interval time of cold bloody cardioplegic solution transfusion during cabg
topic myocardial protection
cardioplegia
coronary sinus
pH
lactate
url http://ismj.bpums.ac.ir/browse.php?a_code=A-10-3-588&slc_lang=en&sid=1
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