Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group.
<h4>Objectives</h4>The risk factors that contribute to future functional disability after heart failure (HF) are poorly understood. The aim of this study was to determine potential risk factors to future functional disability after HF in the general older adult population in Japan.<h4...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0253017&type=printable |
| _version_ | 1826554619887616000 |
|---|---|
| author | Shuko Takahashi Kozo Tanno Yuki Yonekura Masaki Ohsawa Toru Kuribayashi Yasuhiro Ishibashi Shinichi Omama Fumitaka Tanaka Toshiyuki Onoda Kiyomi Sakata Makoto Koshiyama Kazuyoshi Itai Akira Okayama |
| author_facet | Shuko Takahashi Kozo Tanno Yuki Yonekura Masaki Ohsawa Toru Kuribayashi Yasuhiro Ishibashi Shinichi Omama Fumitaka Tanaka Toshiyuki Onoda Kiyomi Sakata Makoto Koshiyama Kazuyoshi Itai Akira Okayama |
| author_sort | Shuko Takahashi |
| collection | DOAJ |
| description | <h4>Objectives</h4>The risk factors that contribute to future functional disability after heart failure (HF) are poorly understood. The aim of this study was to determine potential risk factors to future functional disability after HF in the general older adult population in Japan.<h4>Methods</h4>The subjects who were community-dwelling older adults aged 65 or older without a history of cardiovascular diseases and functional disability were followed in this prospective study for 11 years. Two case groups were determined from the 4,644 subjects: no long-term care insurance (LTCI) after HF (n = 52) and LTCI after HF (n = 44). We selected the controls by randomly matching each case of HF with three of the remaining 4,548 subjects who were event-free during the period: those with no LTCI and no HF with age +/-1 years and of the same sex, control for the no LTCI after HF group (n = 156), and control for the LTCI after HF group (n = 132). HF was diagnosed according to the Framingham diagnostic criteria. Individuals with a functional disability were those who had been newly certified by the LTCI during the observation period. Objective data including blood samples and several socioeconomic items in the baseline survey were assessed using a self-reported questionnaire.<h4>Results</h4>Significantly associated risk factors were lower educational levels (odds ratio (OR) [95% confidence interval (CI)]: 3.72 [1.63-8.48]) in the LTCI after HF group and hypertension (2.20 [1.10-4.43]) in no LTCI after HF group. Regular alcohol consumption and unmarried status were marginally significantly associated with LTCI after HF (OR [95% CI]; drinker = 2.69 [0.95-7.66]; P = 0.063; unmarried status = 2.54 [0.91-7.15]; P = 0.076).<h4>Conclusion</h4>Preventive measures must be taken to protect older adults with unfavorable social factors from disability after HF via a multidisciplinary approach. |
| first_indexed | 2024-12-18T02:17:05Z |
| format | Article |
| id | doaj.art-790148f439f1493784bd89c6496597dd |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2025-03-14T07:43:48Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-790148f439f1493784bd89c6496597dd2025-03-03T05:33:49ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01166e025301710.1371/journal.pone.0253017Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group.Shuko TakahashiKozo TannoYuki YonekuraMasaki OhsawaToru KuribayashiYasuhiro IshibashiShinichi OmamaFumitaka TanakaToshiyuki OnodaKiyomi SakataMakoto KoshiyamaKazuyoshi ItaiAkira Okayama<h4>Objectives</h4>The risk factors that contribute to future functional disability after heart failure (HF) are poorly understood. The aim of this study was to determine potential risk factors to future functional disability after HF in the general older adult population in Japan.<h4>Methods</h4>The subjects who were community-dwelling older adults aged 65 or older without a history of cardiovascular diseases and functional disability were followed in this prospective study for 11 years. Two case groups were determined from the 4,644 subjects: no long-term care insurance (LTCI) after HF (n = 52) and LTCI after HF (n = 44). We selected the controls by randomly matching each case of HF with three of the remaining 4,548 subjects who were event-free during the period: those with no LTCI and no HF with age +/-1 years and of the same sex, control for the no LTCI after HF group (n = 156), and control for the LTCI after HF group (n = 132). HF was diagnosed according to the Framingham diagnostic criteria. Individuals with a functional disability were those who had been newly certified by the LTCI during the observation period. Objective data including blood samples and several socioeconomic items in the baseline survey were assessed using a self-reported questionnaire.<h4>Results</h4>Significantly associated risk factors were lower educational levels (odds ratio (OR) [95% confidence interval (CI)]: 3.72 [1.63-8.48]) in the LTCI after HF group and hypertension (2.20 [1.10-4.43]) in no LTCI after HF group. Regular alcohol consumption and unmarried status were marginally significantly associated with LTCI after HF (OR [95% CI]; drinker = 2.69 [0.95-7.66]; P = 0.063; unmarried status = 2.54 [0.91-7.15]; P = 0.076).<h4>Conclusion</h4>Preventive measures must be taken to protect older adults with unfavorable social factors from disability after HF via a multidisciplinary approach.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0253017&type=printable |
| spellingShingle | Shuko Takahashi Kozo Tanno Yuki Yonekura Masaki Ohsawa Toru Kuribayashi Yasuhiro Ishibashi Shinichi Omama Fumitaka Tanaka Toshiyuki Onoda Kiyomi Sakata Makoto Koshiyama Kazuyoshi Itai Akira Okayama Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group. PLoS ONE |
| title | Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group. |
| title_full | Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group. |
| title_fullStr | Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group. |
| title_full_unstemmed | Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group. |
| title_short | Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group. |
| title_sort | low educational level increases functional disability risk subsequent to heart failure in japan on behalf of the iwate kenco study group |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0253017&type=printable |
| work_keys_str_mv | AT shukotakahashi loweducationallevelincreasesfunctionaldisabilityrisksubsequenttoheartfailureinjapanonbehalfoftheiwatekencostudygroup AT kozotanno loweducationallevelincreasesfunctionaldisabilityrisksubsequenttoheartfailureinjapanonbehalfoftheiwatekencostudygroup AT yukiyonekura loweducationallevelincreasesfunctionaldisabilityrisksubsequenttoheartfailureinjapanonbehalfoftheiwatekencostudygroup AT masakiohsawa loweducationallevelincreasesfunctionaldisabilityrisksubsequenttoheartfailureinjapanonbehalfoftheiwatekencostudygroup AT torukuribayashi loweducationallevelincreasesfunctionaldisabilityrisksubsequenttoheartfailureinjapanonbehalfoftheiwatekencostudygroup AT yasuhiroishibashi loweducationallevelincreasesfunctionaldisabilityrisksubsequenttoheartfailureinjapanonbehalfoftheiwatekencostudygroup AT shinichiomama loweducationallevelincreasesfunctionaldisabilityrisksubsequenttoheartfailureinjapanonbehalfoftheiwatekencostudygroup AT fumitakatanaka loweducationallevelincreasesfunctionaldisabilityrisksubsequenttoheartfailureinjapanonbehalfoftheiwatekencostudygroup AT toshiyukionoda loweducationallevelincreasesfunctionaldisabilityrisksubsequenttoheartfailureinjapanonbehalfoftheiwatekencostudygroup AT kiyomisakata loweducationallevelincreasesfunctionaldisabilityrisksubsequenttoheartfailureinjapanonbehalfoftheiwatekencostudygroup AT makotokoshiyama loweducationallevelincreasesfunctionaldisabilityrisksubsequenttoheartfailureinjapanonbehalfoftheiwatekencostudygroup AT kazuyoshiitai loweducationallevelincreasesfunctionaldisabilityrisksubsequenttoheartfailureinjapanonbehalfoftheiwatekencostudygroup AT akiraokayama loweducationallevelincreasesfunctionaldisabilityrisksubsequenttoheartfailureinjapanonbehalfoftheiwatekencostudygroup |