Risk of mortality associated with preexisting chronic diseases and prior year diagnosis of a mental disorder in survivors of a first myocardial infarction or stroke: A cohort study
Background: Chronic medical diseases and recurrent mental disorders are common and may lead to a negative prognosis in adults with cardiovascular diseases (CVDs). The impact of these overlapping morbidities is likely to be further increased in the critical years following a first acute CVD event suc...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Heart and Mind |
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| Online Access: | http://www.heartmindjournal.org/article.asp?issn=2468-6476;year=2023;volume=7;issue=3;spage=164;epage=170;aulast=Ngueta |
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| author | Gerard Ngueta Claudia Blais Guillaume Foldes-Busque Denis Hamel Paul Poirier |
| author_facet | Gerard Ngueta Claudia Blais Guillaume Foldes-Busque Denis Hamel Paul Poirier |
| author_sort | Gerard Ngueta |
| collection | DOAJ |
| description | Background: Chronic medical diseases and recurrent mental disorders are common and may lead to a negative prognosis in adults with cardiovascular diseases (CVDs). The impact of these overlapping morbidities is likely to be further increased in the critical years following a first acute CVD event such as a stroke or myocardial infarction (MI). Objectives: The objective of this study was to examine associations of preexisting chronic diseases and recent mental disorders with mortality in survivors of a first MI or stroke. Methods: Data from the 48,526 patients (59% men) aged ≥40 years with a first MI or stroke were extracted from the Quebec Integrated Chronic Disease Surveillance System. Cox regression models were used to assess the effect of preexisting cancer, renal disease, diabetes, chronic obstructive pulmonary disease (COPD), and recent mental disorders on the risk of recurrent fatal CVD events and all-cause mortality following the index MI or stroke. Results: An increased risk of CVD mortality was observed at 1, 3, and 4.5 years in women and men with coexisting mental disorders and at 4.5 years in those with chronic, preexisting renal disease. Inversely, cancer and COPD were associated with a lowered risk of CVD mortality during the study period. An increased risk of all-cause mortality at all time points was observed in adults with any of the assessed conditions. Conclusions: Adults with coexisting mental disorders are at increased risk of CVD mortality and all-cause mortality in the years following a first MI or stroke. This increased vulnerability is separate from the extra mortality attributable to preexisting chronic diseases. |
| first_indexed | 2024-03-11T15:46:07Z |
| format | Article |
| id | doaj.art-7901ce4c74ea40f5bae2d109337f5dd9 |
| institution | Directory Open Access Journal |
| issn | 2468-6476 2468-6484 |
| language | English |
| last_indexed | 2024-03-11T15:46:07Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Heart and Mind |
| spelling | doaj.art-7901ce4c74ea40f5bae2d109337f5dd92023-10-26T06:27:53ZengWolters Kluwer Medknow PublicationsHeart and Mind2468-64762468-64842023-01-017316417010.4103/hm.HM-D-23-00022Risk of mortality associated with preexisting chronic diseases and prior year diagnosis of a mental disorder in survivors of a first myocardial infarction or stroke: A cohort studyGerard NguetaClaudia BlaisGuillaume Foldes-BusqueDenis HamelPaul PoirierBackground: Chronic medical diseases and recurrent mental disorders are common and may lead to a negative prognosis in adults with cardiovascular diseases (CVDs). The impact of these overlapping morbidities is likely to be further increased in the critical years following a first acute CVD event such as a stroke or myocardial infarction (MI). Objectives: The objective of this study was to examine associations of preexisting chronic diseases and recent mental disorders with mortality in survivors of a first MI or stroke. Methods: Data from the 48,526 patients (59% men) aged ≥40 years with a first MI or stroke were extracted from the Quebec Integrated Chronic Disease Surveillance System. Cox regression models were used to assess the effect of preexisting cancer, renal disease, diabetes, chronic obstructive pulmonary disease (COPD), and recent mental disorders on the risk of recurrent fatal CVD events and all-cause mortality following the index MI or stroke. Results: An increased risk of CVD mortality was observed at 1, 3, and 4.5 years in women and men with coexisting mental disorders and at 4.5 years in those with chronic, preexisting renal disease. Inversely, cancer and COPD were associated with a lowered risk of CVD mortality during the study period. An increased risk of all-cause mortality at all time points was observed in adults with any of the assessed conditions. Conclusions: Adults with coexisting mental disorders are at increased risk of CVD mortality and all-cause mortality in the years following a first MI or stroke. This increased vulnerability is separate from the extra mortality attributable to preexisting chronic diseases.http://www.heartmindjournal.org/article.asp?issn=2468-6476;year=2023;volume=7;issue=3;spage=164;epage=170;aulast=Nguetacardiovascular deathchronic conditionsmental disordermortalitymultimorbidity |
| spellingShingle | Gerard Ngueta Claudia Blais Guillaume Foldes-Busque Denis Hamel Paul Poirier Risk of mortality associated with preexisting chronic diseases and prior year diagnosis of a mental disorder in survivors of a first myocardial infarction or stroke: A cohort study Heart and Mind cardiovascular death chronic conditions mental disorder mortality multimorbidity |
| title | Risk of mortality associated with preexisting chronic diseases and prior year diagnosis of a mental disorder in survivors of a first myocardial infarction or stroke: A cohort study |
| title_full | Risk of mortality associated with preexisting chronic diseases and prior year diagnosis of a mental disorder in survivors of a first myocardial infarction or stroke: A cohort study |
| title_fullStr | Risk of mortality associated with preexisting chronic diseases and prior year diagnosis of a mental disorder in survivors of a first myocardial infarction or stroke: A cohort study |
| title_full_unstemmed | Risk of mortality associated with preexisting chronic diseases and prior year diagnosis of a mental disorder in survivors of a first myocardial infarction or stroke: A cohort study |
| title_short | Risk of mortality associated with preexisting chronic diseases and prior year diagnosis of a mental disorder in survivors of a first myocardial infarction or stroke: A cohort study |
| title_sort | risk of mortality associated with preexisting chronic diseases and prior year diagnosis of a mental disorder in survivors of a first myocardial infarction or stroke a cohort study |
| topic | cardiovascular death chronic conditions mental disorder mortality multimorbidity |
| url | http://www.heartmindjournal.org/article.asp?issn=2468-6476;year=2023;volume=7;issue=3;spage=164;epage=170;aulast=Ngueta |
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