Identification of epigenetic modulators in human breast cancer by integrated analysis of DNA methylation and RNA-Seq data

Identification of epigenetic modulators in human breast cancer by integrated analysis of DNA methylation and RNA-Seq data

Human tumors undergo massive changes in DNA methylation. Recent studies showed that site-specific methylation of CpG sites is determined by the DNA sequence context surrounding the CpG site, which alludes to a possible mechanism for site-specific aberrant DNA methylation in cancer through DNA-bindin...

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Bibliographic Details
Main Authors: Xin Zhou, Zhibin Chen, Xiaodong Cai
Format: Article
Language:English
Published: Taylor & Francis Group 2018-05-01
Series:Epigenetics
Subjects:
dna methylation
breast cancer
epigenetic modulator
dna motif
dna-binding protein
gene network
Online Access:http://dx.doi.org/10.1080/15592294.2018.1469894

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