Analyze on the value of conjunctival impression cytology in the diagnosis of allergic conjunctivitis

AIM: To investigate the value of conjunctival impression cytology(CIC)in the diagnosis of allergic conjunctivitis(AC). METHODS: A case-control study. Forty patients(80 eyes)who were clinically diagnosed with AC in our department from January to February 2021 were included in the study,and 40 normal...

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Main Authors: Ni Yin, Xiang-Hua Xiao, Hua Yang, Xian-Ning Liu, Chao Liu, Hai-Qing Lu, Jin-Xin Song
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2022-05-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2022/5/202205038.pdf
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author Ni Yin
Xiang-Hua Xiao
Hua Yang
Xian-Ning Liu
Chao Liu
Hai-Qing Lu
Jin-Xin Song
author_facet Ni Yin
Xiang-Hua Xiao
Hua Yang
Xian-Ning Liu
Chao Liu
Hai-Qing Lu
Jin-Xin Song
author_sort Ni Yin
collection DOAJ
description AIM: To investigate the value of conjunctival impression cytology(CIC)in the diagnosis of allergic conjunctivitis(AC). METHODS: A case-control study. Forty patients(80 eyes)who were clinically diagnosed with AC in our department from January to February 2021 were included in the study,and 40 normal controls(80 eyes)were enrolled too. All subjects underwent double upper palpebral CIC examinations. Observed the morphology and number of conjunctival eosinophils and carried out Tseng classification in each group. To Compare the differences between the results of the two groups and analyze the effects of gender, age and course of disease on the results of CIC eosinophil examination in AC group.RESULTS: The positive rate of eosinophils in the upper palpebral CIC examination of AC patients was significantly higher than that of the normal control group(χ2=57.744, P<0.001); The Tseng grade of AC patients was also higher than that of the normal control group(Z=-2.453, P<0.05). Gender, age and course of disease had no significant effect on the results of CIC eosinophils in AC group(all P >0.05).CONCLUSION: CIC examination is simple, and the result is objective and accurate. It has good application value in the diagnosis of AC.
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spelling doaj.art-790268de30a0451da5e030a766cd3a0a2022-12-22T00:11:11ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232022-05-0122588488610.3980/j.issn.1672-5123.2022.5.38202205038Analyze on the value of conjunctival impression cytology in the diagnosis of allergic conjunctivitisNi Yin0Xiang-Hua Xiao1Hua Yang2Xian-Ning Liu3Chao Liu4Hai-Qing Lu5Jin-Xin Song6The Institute of Ophthalmology, Xi'an No.1 Hospital;Shaanxi Institute of Ophthalmology;Shaanxi Key Laboratory of Ophthalmology;Clinical Research Center for Ophthalmology Diseases of Shaanxi Province;First Affiliated Hospital of Northwest University, Xi'an 710002, Shaanxi Province, ChinaThe Institute of Ophthalmology, Xi'an No.1 Hospital;Shaanxi Institute of Ophthalmology;Shaanxi Key Laboratory of Ophthalmology;Clinical Research Center for Ophthalmology Diseases of Shaanxi Province;First Affiliated Hospital of Northwest University, Xi'an 710002, Shaanxi Province, ChinaThe Institute of Ophthalmology, Xi'an No.1 Hospital;Shaanxi Institute of Ophthalmology;Shaanxi Key Laboratory of Ophthalmology;Clinical Research Center for Ophthalmology Diseases of Shaanxi Province;First Affiliated Hospital of Northwest University, Xi'an 710002, Shaanxi Province, ChinaThe Institute of Ophthalmology, Xi'an No.1 Hospital;Shaanxi Institute of Ophthalmology;Shaanxi Key Laboratory of Ophthalmology;Clinical Research Center for Ophthalmology Diseases of Shaanxi Province;First Affiliated Hospital of Northwest University, Xi'an 710002, Shaanxi Province, ChinaThe Institute of Ophthalmology, Xi'an No.1 Hospital;Shaanxi Institute of Ophthalmology;Shaanxi Key Laboratory of Ophthalmology;Clinical Research Center for Ophthalmology Diseases of Shaanxi Province;First Affiliated Hospital of Northwest University, Xi'an 710002, Shaanxi Province, ChinaThe Institute of Ophthalmology, Xi'an No.1 Hospital;Shaanxi Institute of Ophthalmology;Shaanxi Key Laboratory of Ophthalmology;Clinical Research Center for Ophthalmology Diseases of Shaanxi Province;First Affiliated Hospital of Northwest University, Xi'an 710002, Shaanxi Province, ChinaThe Institute of Ophthalmology, Xi'an No.1 Hospital;Shaanxi Institute of Ophthalmology;Shaanxi Key Laboratory of Ophthalmology;Clinical Research Center for Ophthalmology Diseases of Shaanxi Province;First Affiliated Hospital of Northwest University, Xi'an 710002, Shaanxi Province, ChinaAIM: To investigate the value of conjunctival impression cytology(CIC)in the diagnosis of allergic conjunctivitis(AC). METHODS: A case-control study. Forty patients(80 eyes)who were clinically diagnosed with AC in our department from January to February 2021 were included in the study,and 40 normal controls(80 eyes)were enrolled too. All subjects underwent double upper palpebral CIC examinations. Observed the morphology and number of conjunctival eosinophils and carried out Tseng classification in each group. To Compare the differences between the results of the two groups and analyze the effects of gender, age and course of disease on the results of CIC eosinophil examination in AC group.RESULTS: The positive rate of eosinophils in the upper palpebral CIC examination of AC patients was significantly higher than that of the normal control group(χ2=57.744, P<0.001); The Tseng grade of AC patients was also higher than that of the normal control group(Z=-2.453, P<0.05). Gender, age and course of disease had no significant effect on the results of CIC eosinophils in AC group(all P >0.05).CONCLUSION: CIC examination is simple, and the result is objective and accurate. It has good application value in the diagnosis of AC.http://ies.ijo.cn/cn_publish/2022/5/202205038.pdfallergyallergic conjunctivitisimpression cytologyeosinophilsdry eye
spellingShingle Ni Yin
Xiang-Hua Xiao
Hua Yang
Xian-Ning Liu
Chao Liu
Hai-Qing Lu
Jin-Xin Song
Analyze on the value of conjunctival impression cytology in the diagnosis of allergic conjunctivitis
Guoji Yanke Zazhi
allergy
allergic conjunctivitis
impression cytology
eosinophils
dry eye
title Analyze on the value of conjunctival impression cytology in the diagnosis of allergic conjunctivitis
title_full Analyze on the value of conjunctival impression cytology in the diagnosis of allergic conjunctivitis
title_fullStr Analyze on the value of conjunctival impression cytology in the diagnosis of allergic conjunctivitis
title_full_unstemmed Analyze on the value of conjunctival impression cytology in the diagnosis of allergic conjunctivitis
title_short Analyze on the value of conjunctival impression cytology in the diagnosis of allergic conjunctivitis
title_sort analyze on the value of conjunctival impression cytology in the diagnosis of allergic conjunctivitis
topic allergy
allergic conjunctivitis
impression cytology
eosinophils
dry eye
url http://ies.ijo.cn/cn_publish/2022/5/202205038.pdf
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