T-Cell Depleted Haploidentical Transplantation in Children With Hematological Malignancies: A Comparison Between CD3+/CD19+ and TCRαβ+/CD19+ Depletion Platforms

T-Cell Depleted Haploidentical Transplantation in Children With Hematological Malignancies: A Comparison Between CD3+/CD19+ and TCRαβ+/CD19+ Depletion Platforms

BackgroundT-cell depleted (TCD) haploidentical transplantation using CD3+/CD19+ and TCRαβ+/CD19+ depletion techniques has been increasingly used in children with hematological malignancies. We present a retrospective study aimed to compare transplant outcomes in children with leukemia receiving a TC...

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Bibliographic Details
Main Authors: Marta Gonzalez-Vicent, Blanca Molina, Ivan Lopez, Josune Zubicaray, Julia Ruiz, Jose Luis Vicario, Elena Sebastián, June Iriondo, Ana Castillo, Lorea Abad, Manuel Ramirez, Julian Sevilla, Miguel A. Diaz
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
haploidentical transplant
hematological malignancies
immune reconstitution
children
T-cell depletion
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.884397/full

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