Association of Mean Arterial Pressure during Cardiopulmonary Pump and Incidence of Delirium after Coronary Artery Bypass Graft Surgery

Background: Despite improved outcomes after cardiac operations, delirium is a common neurologic complication after cardiac surgery. In this study, we aimed to investigate the association of postoperative delirium and mean arterial pressure (MAP) during cardiopulmonary pump in patients after coronary...

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Main Authors: Keyvan Bagheri, Azim Honarmand, Seyed Jamaleddin Hosseini-Moosa
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2017-12-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/8069
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author Keyvan Bagheri
Azim Honarmand
Seyed Jamaleddin Hosseini-Moosa
author_facet Keyvan Bagheri
Azim Honarmand
Seyed Jamaleddin Hosseini-Moosa
author_sort Keyvan Bagheri
collection DOAJ
description Background: Despite improved outcomes after cardiac operations, delirium is a common neurologic complication after cardiac surgery. In this study, we aimed to investigate the association of postoperative delirium and mean arterial pressure (MAP) during cardiopulmonary pump in patients after coronary artery bypass graft (CABG). Methods: 100 inpatients submitted to coronary artery bypass graft were evaluated prior to and after surgery. In order to investigate the association between mean arterial pressure and incidence of delirium, data were collected at pre intra, and postoperative periods. The patients were examined for delirium using Mini-Mental State Examination (MMSE). Findings: Preoperative delirium was detected in 34 patients (34%) and 74 patients (74%) had postoperative delirium. There was a significant positive correlation between total score of MMSE and mean arterial pressure during cardiopulmonary pump (r = +0.22, P = 0.02). Furthermore, there was a significant correlation between total score of MMSE and O2 saturation (r = +0.22, P = 0.03). Conclusion: Present study suggests associations between incidence of postoperative delirium and mean arterial pressure and O2 saturation during cardiopulmonary pump. Maintaining mean arterial pressure and O2 saturation of blood at physiologic levels during cardiopulmonary pump may be associated with less early postoperative delirium and cognitive dysfunction.
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spelling doaj.art-790899b0038f4d2e95eb7f9353e2cece2023-09-02T09:54:09ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2017-12-0135449135813632679Association of Mean Arterial Pressure during Cardiopulmonary Pump and Incidence of Delirium after Coronary Artery Bypass Graft SurgeryKeyvan Bagheri0Azim Honarmand1Seyed Jamaleddin Hosseini-Moosa2Assistant Professor, Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranAssociate Professor, Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranStudent of Medicine, School of Medicine, Student Research Committee, Isfahan University of Medical Sciences, Isfahan, IranBackground: Despite improved outcomes after cardiac operations, delirium is a common neurologic complication after cardiac surgery. In this study, we aimed to investigate the association of postoperative delirium and mean arterial pressure (MAP) during cardiopulmonary pump in patients after coronary artery bypass graft (CABG). Methods: 100 inpatients submitted to coronary artery bypass graft were evaluated prior to and after surgery. In order to investigate the association between mean arterial pressure and incidence of delirium, data were collected at pre intra, and postoperative periods. The patients were examined for delirium using Mini-Mental State Examination (MMSE). Findings: Preoperative delirium was detected in 34 patients (34%) and 74 patients (74%) had postoperative delirium. There was a significant positive correlation between total score of MMSE and mean arterial pressure during cardiopulmonary pump (r = +0.22, P = 0.02). Furthermore, there was a significant correlation between total score of MMSE and O2 saturation (r = +0.22, P = 0.03). Conclusion: Present study suggests associations between incidence of postoperative delirium and mean arterial pressure and O2 saturation during cardiopulmonary pump. Maintaining mean arterial pressure and O2 saturation of blood at physiologic levels during cardiopulmonary pump may be associated with less early postoperative delirium and cognitive dysfunction.http://jims.mui.ac.ir/index.php/jims/article/view/8069Coronary artery bypass graftingDeliriumMean arterial pressure
spellingShingle Keyvan Bagheri
Azim Honarmand
Seyed Jamaleddin Hosseini-Moosa
Association of Mean Arterial Pressure during Cardiopulmonary Pump and Incidence of Delirium after Coronary Artery Bypass Graft Surgery
مجله دانشکده پزشکی اصفهان
Coronary artery bypass grafting
Delirium
Mean arterial pressure
title Association of Mean Arterial Pressure during Cardiopulmonary Pump and Incidence of Delirium after Coronary Artery Bypass Graft Surgery
title_full Association of Mean Arterial Pressure during Cardiopulmonary Pump and Incidence of Delirium after Coronary Artery Bypass Graft Surgery
title_fullStr Association of Mean Arterial Pressure during Cardiopulmonary Pump and Incidence of Delirium after Coronary Artery Bypass Graft Surgery
title_full_unstemmed Association of Mean Arterial Pressure during Cardiopulmonary Pump and Incidence of Delirium after Coronary Artery Bypass Graft Surgery
title_short Association of Mean Arterial Pressure during Cardiopulmonary Pump and Incidence of Delirium after Coronary Artery Bypass Graft Surgery
title_sort association of mean arterial pressure during cardiopulmonary pump and incidence of delirium after coronary artery bypass graft surgery
topic Coronary artery bypass grafting
Delirium
Mean arterial pressure
url http://jims.mui.ac.ir/index.php/jims/article/view/8069
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