Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report
Introduction: This study is a case of solitary clear cell renal cell carcinoma (ccRCC) eyelid metastasis in a 66-year-old man as the first sign of a primary tumor. ccRCC usually spreads to the lungs, mediastinum, bones, liver, and brain, while ocular metastases are rare. Case Presentation: Solitary...
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Format: | Article |
Language: | English |
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Karger Publishers
2024-03-01
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Series: | Case Reports in Oncology |
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Online Access: | https://beta.karger.com/Article/FullText/537860 |
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author | Ognjen Zrinšćak Armin Kasumović Iva Krolo Renata Ivekovic Maja Malenica Ravlić Igor Tomašković Zoran Vatavuk |
author_facet | Ognjen Zrinšćak Armin Kasumović Iva Krolo Renata Ivekovic Maja Malenica Ravlić Igor Tomašković Zoran Vatavuk |
author_sort | Ognjen Zrinšćak |
collection | DOAJ |
description | Introduction: This study is a case of solitary clear cell renal cell carcinoma (ccRCC) eyelid metastasis in a 66-year-old man as the first sign of a primary tumor. ccRCC usually spreads to the lungs, mediastinum, bones, liver, and brain, while ocular metastases are rare. Case Presentation: Solitary metastasis presented as a solid mass in the central third of the upper eyelid, which has been growing for 3 weeks. Treatment included tumor removal and blepharoplasty. Histopathological examination showed metastasis of clear cell renal carcinoma. A thorough examination revealed a primary tumor on the lower pole of the right kidney. A right nephrectomy was performed, and histopathology showed ccRCC. Postoperative examinations showed no signs of local or systemic disease. Sunitinib malate was administered to the patient. Conclusion: The eyelid metastasis in this case was still solitary and had been discovered before the existence of the primary tumor was known. Ocular metastasis of renal carcinoma is a rare initial manifestation of the disease and therefore requires a multidisciplinary approach in the treatment of these patients. |
first_indexed | 2024-04-24T07:54:28Z |
format | Article |
id | doaj.art-790b224c6b824ff1b2e94dba4c3eb476 |
institution | Directory Open Access Journal |
issn | 1662-6575 |
language | English |
last_indexed | 2024-04-24T07:54:28Z |
publishDate | 2024-03-01 |
publisher | Karger Publishers |
record_format | Article |
series | Case Reports in Oncology |
spelling | doaj.art-790b224c6b824ff1b2e94dba4c3eb4762024-04-18T07:17:48ZengKarger PublishersCase Reports in Oncology1662-65752024-03-0117147748310.1159/000537860537860Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case ReportOgnjen Zrinšćak0Armin Kasumović1Iva Krolo2Renata Ivekovic3Maja Malenica Ravlić4Igor Tomašković5Zoran Vatavuk6University Department of Ophthalmology and Optometry, University Hospital Center, Sestre milosrdnice, Zagreb, CroatiaUniversity Department of Ophthalmology and Optometry, University Hospital Center, Sestre milosrdnice, Zagreb, CroatiaUniversity Department of Ophthalmology, University Hospital Brussels, Brussels (UZ Brussel), Jette, BelgiumUniversity Department of Ophthalmology and Optometry, University Hospital Center, Sestre milosrdnice, Zagreb, CroatiaUniversity Department of Ophthalmology and Optometry, University Hospital Center, Sestre milosrdnice, Zagreb, CroatiaUniversity Department of Urology, University Hospital Center, Sestre milosrdnice, Zagreb, CroatiaUniversity Department of Ophthalmology and Optometry, University Hospital Center, Sestre milosrdnice, Zagreb, CroatiaIntroduction: This study is a case of solitary clear cell renal cell carcinoma (ccRCC) eyelid metastasis in a 66-year-old man as the first sign of a primary tumor. ccRCC usually spreads to the lungs, mediastinum, bones, liver, and brain, while ocular metastases are rare. Case Presentation: Solitary metastasis presented as a solid mass in the central third of the upper eyelid, which has been growing for 3 weeks. Treatment included tumor removal and blepharoplasty. Histopathological examination showed metastasis of clear cell renal carcinoma. A thorough examination revealed a primary tumor on the lower pole of the right kidney. A right nephrectomy was performed, and histopathology showed ccRCC. Postoperative examinations showed no signs of local or systemic disease. Sunitinib malate was administered to the patient. Conclusion: The eyelid metastasis in this case was still solitary and had been discovered before the existence of the primary tumor was known. Ocular metastasis of renal carcinoma is a rare initial manifestation of the disease and therefore requires a multidisciplinary approach in the treatment of these patients.https://beta.karger.com/Article/FullText/537860eyelid tumoreye metastasisrenal carcinoma |
spellingShingle | Ognjen Zrinšćak Armin Kasumović Iva Krolo Renata Ivekovic Maja Malenica Ravlić Igor Tomašković Zoran Vatavuk Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report Case Reports in Oncology eyelid tumor eye metastasis renal carcinoma |
title | Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report |
title_full | Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report |
title_fullStr | Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report |
title_full_unstemmed | Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report |
title_short | Solitary Clear Cell Renal Cell Carcinoma Metastasis to the Eyelid: A Case Report |
title_sort | solitary clear cell renal cell carcinoma metastasis to the eyelid a case report |
topic | eyelid tumor eye metastasis renal carcinoma |
url | https://beta.karger.com/Article/FullText/537860 |
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