Reduction of Compton Background Noise for X-ray Fluorescence Computed Tomography with Deep Learning

For bench-top X-ray fluorescence computed tomography (XFCT), the X-ray tube source will bring extreme Compton background noise, resulting in a low signal-to-noise ratio and low contrast detection limit. In this paper, a noise2noise denoising algorithm based on the UNet deep learning network is propo...

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Main Authors: Peng Feng, Yan Luo, Ruge Zhao, Pan Huang, Yonghui Li, Peng He, Bin Tang, Xiansheng Zhao
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Photonics
Subjects:
Online Access:https://www.mdpi.com/2304-6732/9/2/108
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author Peng Feng
Yan Luo
Ruge Zhao
Pan Huang
Yonghui Li
Peng He
Bin Tang
Xiansheng Zhao
author_facet Peng Feng
Yan Luo
Ruge Zhao
Pan Huang
Yonghui Li
Peng He
Bin Tang
Xiansheng Zhao
author_sort Peng Feng
collection DOAJ
description For bench-top X-ray fluorescence computed tomography (XFCT), the X-ray tube source will bring extreme Compton background noise, resulting in a low signal-to-noise ratio and low contrast detection limit. In this paper, a noise2noise denoising algorithm based on the UNet deep learning network is proposed. The network can use noise image learning to convert the noise image into a clean image. Two sets of phantoms (high concentration Gd phantom and low concentration Bi phantom) are used for scanning to simulate the imaging process under different noise levels and generate the required data set. Additionally, the data set is generated by Geant4 simulation. In the training process, the L1 loss function is used for its good convergence. The image quality is evaluated according to CNR and pixel profile, which shows that our algorithm is better than BM3D, both visually and quantitatively.
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spelling doaj.art-790bf6cdd5eb4dc6a46308ff759e33362023-11-23T21:41:37ZengMDPI AGPhotonics2304-67322022-02-019210810.3390/photonics9020108Reduction of Compton Background Noise for X-ray Fluorescence Computed Tomography with Deep LearningPeng Feng0Yan Luo1Ruge Zhao2Pan Huang3Yonghui Li4Peng He5Bin Tang6Xiansheng Zhao7The Key Lab of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing 400044, ChinaThe Key Lab of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing 400044, ChinaThe Key Lab of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing 400044, ChinaThe Key Lab of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing 400044, ChinaThe Key Lab of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing 400044, ChinaThe Key Lab of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing 400044, ChinaThe Key Lab of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing 400044, ChinaThe Key Lab of Optoelectronic Technology and Systems, Ministry of Education, Chongqing University, Chongqing 400044, ChinaFor bench-top X-ray fluorescence computed tomography (XFCT), the X-ray tube source will bring extreme Compton background noise, resulting in a low signal-to-noise ratio and low contrast detection limit. In this paper, a noise2noise denoising algorithm based on the UNet deep learning network is proposed. The network can use noise image learning to convert the noise image into a clean image. Two sets of phantoms (high concentration Gd phantom and low concentration Bi phantom) are used for scanning to simulate the imaging process under different noise levels and generate the required data set. Additionally, the data set is generated by Geant4 simulation. In the training process, the L1 loss function is used for its good convergence. The image quality is evaluated according to CNR and pixel profile, which shows that our algorithm is better than BM3D, both visually and quantitatively.https://www.mdpi.com/2304-6732/9/2/108XFCTCompton background noiseUNet networknoise2noise model
spellingShingle Peng Feng
Yan Luo
Ruge Zhao
Pan Huang
Yonghui Li
Peng He
Bin Tang
Xiansheng Zhao
Reduction of Compton Background Noise for X-ray Fluorescence Computed Tomography with Deep Learning
Photonics
XFCT
Compton background noise
UNet network
noise2noise model
title Reduction of Compton Background Noise for X-ray Fluorescence Computed Tomography with Deep Learning
title_full Reduction of Compton Background Noise for X-ray Fluorescence Computed Tomography with Deep Learning
title_fullStr Reduction of Compton Background Noise for X-ray Fluorescence Computed Tomography with Deep Learning
title_full_unstemmed Reduction of Compton Background Noise for X-ray Fluorescence Computed Tomography with Deep Learning
title_short Reduction of Compton Background Noise for X-ray Fluorescence Computed Tomography with Deep Learning
title_sort reduction of compton background noise for x ray fluorescence computed tomography with deep learning
topic XFCT
Compton background noise
UNet network
noise2noise model
url https://www.mdpi.com/2304-6732/9/2/108
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